Dietmar Zaiss
Contact details
- Tel: +44 (0)131 651 7780
- Email: Dietmar.Zaiss@ed.ac.uk
Address
- Street
-
Rm. 3.11, Ashworth building
- City
- Post code
Background
2017 - current Reader in Immunology, University of Edinburgh / Institute of Immunology and Infection Research
2013 - 2017 Lecturer in Immunology and Chancellor's Fellow, University of Edinburgh / Institute of Immunology and Infection Research
2006 - 2013 Group Leader, University of Utrecht, The Netherlands, Faculty of Veterinary Medicine (Immunology)
2002 - 2005 Post-Doc, University of Rochester, NY, USA- Dr. Tim Mosmann (Immunology)
1996 - 2000 Ph.D., Humboldt University, Berlin - Dr. P-M. Kloetzel (Cell Biology)
1993 - 1996 M.Sc. Syracuse University, NY, USA - Dr. John Belote (Cell and Molecular Biology)
Undergraduate teaching
Course Organizer “Clinical Immunology & Haematology” CI&H-3 (co-chaired together with Julia Dorin) for Third-Year / “Junior Honours” students. This course runs during the Spring semester
Participates in the courses
- “Molecules, Infection and Immunity” (MII-2) for Second-Year students, which runs during the Spring semester.
- “Immunology - 3” for Third-Year students, course runs during the Autumn semester.
- “Molecular Immunology” and “Immunobiology” for Forth-Year / “Immunology Honours” students, courses run during the Autumn semester.
- Master Course "Vaccines and Molecular Therapies", during the Spring semester
In addition, organises a weekly, department-internal “Immunology Refresher Training” for post-graduate students & supervises lab-based, scientific 10 weeks “Honours Projects”
-
Nemo-like kinase drives Foxp3 stability and is critical for maintenance of immune tolerance by regulatory T cells
(20 pages)
In:
Cell Reports, vol. 26, no. 13, pp. 3600-3612
DOI: https://doi.org/10.1016/j.celrep.2019.02.087
Contribution to journal › Article (Published) -
A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation
(16 pages)
In:
Immunity, vol. 50
DOI: https://doi.org/10.1016/j.immuni.2019.01.008
Contribution to journal › Article (Published) -
Immune and non-immune mediated roles of regulatory T-cells during wound healing
In:
Immunology
DOI: https://doi.org/10.1111/imm.13057
Contribution to journal › Review article (E-pub ahead of print) -
Forkhead box transcription factors as context-dependent regulators of lymphocyte homeostasis
(13 pages)
In:
Nature Reviews Immunology
DOI: https://doi.org/10.1038/s41577-018-0048-9
Contribution to journal › Review article (E-pub ahead of print) -
Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth
(14 pages)
In:
Breast Cancer Research, vol. 20, no. 1, pp. 131
DOI: https://doi.org/10.1186/s13058-018-1057-0
Contribution to journal › Article (Published) -
Amphiregulin-producing γδ T cells are vital for safeguarding oral barrier immune homeostasis
(6 pages)
In:
Proceedings of the National Academy of Sciences, vol. 115, no. 42, pp. 10738-10743
DOI: https://doi.org/10.1073/pnas.1802320115
Contribution to journal › Article (Published) -
The immune system’s contribution to the clinical efficacy of EGFR antagonist treatment
(7 pages)
In:
Frontiers in pharmacology, vol. 8, pp. 1-7
DOI: https://doi.org/10.3389/fphar.2017.00575
Contribution to journal › Review article (Published) -
Local amplifiers of IL-4Rα–mediated macrophage activation promote repair in lung and liver
In:
Science, vol. 356, no. 6342, pp. 1076 - 1080
DOI: https://doi.org/10.1126/science.aaj2067
Contribution to journal › Article (Published) -
Dissecting antigen processing and presentation routes in dermal vaccination strategies
(7 pages)
In:
Vaccine, vol. 35, no. 50, pp. 7057-7063
DOI: https://doi.org/10.1016/j.vaccine.2017.10.044
Contribution to journal › Article (Published) -
Epidermal growth factor receptor expression licenses T helper-2 cells to function in a T cell receptor-independent fashion
(13 pages)
In:
Immunity, vol. 47, pp. 710-722
DOI: https://doi.org/10.1016/j.immuni.2017.09.013
Contribution to journal › Article (Published) -
Type 2 Innate Lymphoid Cells Treat and Prevent GI Tract GvHD Through Enhanced Accumulation of Myeloid Derived Suppressor Cells
In:
Journal of Clinical Investigation
DOI: https://doi.org/10.1172/JCI91816
Contribution to journal › Article (Published) -
Tissue-specific contribution of macrophages to wound healing
(9 pages)
In:
Seminars in Cell and Developmental Biology
DOI: https://doi.org/10.1016/j.semcdb.2016.08.006
Contribution to journal › Article (Published) -
IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin-EGFR interactions
(6 pages)
In:
Proceedings of the National Academy of Sciences, vol. 112, no. 34, pp. 10762-10767
DOI: https://doi.org/10.1073/pnas.1509070112
Contribution to journal › Article (Published) -
Allergen-specific cytokine polarization protects Shetland ponies against Culicoides obsoletus-induced insect bite hypersensitivity
In:
PLoS ONE, vol. 10, no. 4
DOI: https://doi.org/10.1371/journal.pone.0122090
Contribution to journal › Article (Published) -
Emerging Functions of Amphiregulin in Orchestrating Immunity, Inflammation, and Tissue Repair
(11 pages)
In:
Immunity, vol. 42, no. 2, pp. 216-226
DOI: https://doi.org/10.1016/j.immuni.2015.01.020
Contribution to journal › Article (Published) -
Enhanced Inflammatory Potential of CD4(+) T-Cells That Lack Proteasome Immunosubunit Expression, in a T-Cell Transfer-Based Colitis Model
(7 pages)
In:
PLoS ONE, vol. 9, no. 4
DOI: https://doi.org/10.1371/journal.pone.0095378
Contribution to journal › Article (Published) -
Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity
(13 pages)
In:
Immunity, vol. 39, no. 2, pp. 259-71
DOI: https://doi.org/10.1016/j.immuni.2013.05.018
Contribution to journal › Article (Published) -
Canonical Wnt signaling negatively modulates regulatory T cell function
(13 pages)
In:
Immunity, vol. 39, no. 2, pp. 298-310
DOI: https://doi.org/10.1016/j.immuni.2013.07.019
Contribution to journal › Article (Published) -
Amphiregulin Enhances Regulatory T Cell-Suppressive Function via the Epidermal Growth Factor Receptor
(10 pages)
In:
Immunity, vol. 38, no. 2, pp. 275-284
DOI: https://doi.org/10.1016/j.immuni.2012.09.023
Contribution to journal › Article (Published) -
Pre-existing virus-specific CD8+ T-cells provide protection against pneumovirus-induced disease in mice
(7 pages)
In:
Vaccine, vol. 30, no. 45, pp. 6382-6388
DOI: https://doi.org/10.1016/j.vaccine.2012.08.027
Contribution to journal › Article (Published)