Dr Diego Robledo
Career Track Fellow
Contact details
Address
- Street
-
The Roslin Institute, Easter Bush Campus, University of Edinburgh
- City
- Midlothian
- Post code
- EH25 9RG
Background
Scinetist in aquaculture genetics & genomics at the Roslin Institute.
As an undergraduate I studied biology in the University of Santiago de Compostela (Galicia, NW Spain). During my PhD in the genetics department of the same university I studied sex determination in turbot, but also had the opportunity to work in other traits and species, generally developing genomic resources and studying immune responses to pathogens. For my postdoc I moved to the Roslin Institute where I complemented my expertise in functional genomics with skills on quantitative genetics and animal breeding, and applied them to study resistance to various diseases in Atlantic salmon. Since 2019 I am a group leader developing my research ideas at the Roslin Institute, or at least trying to!
- [2019-Present] Roslin Fellow (The Roslin Institute)
- [2017-2019] Royal society Newton International Fellow (The Roslin Institute)
- [2016-2017] Postdoctoral research fellow (The Roslin Institute)
- [2011-2016] PhD in Genetics (University of Santiago de Compostela)
Open to PhD supervision enquiries?
Yes
Areas of interest for supervision
Always open to discuss opportunities in our research group. The main criteria is to be nice and friendly. If you meet these criteria, please feel free to get in touch!
Research summary
My main interest is to understand responses to pathogens in aquaculture species. I use functional genomics to understand differences in resistance / susceptibility and learn about the genomic mechanisms underpinning successful immune responses. The final goal is to exploit this knowledge to produce disease resistant animals through genome editing and genomic selection.
My research involves the whole range of genetic and genomic technologies, including genome assemblies and other genomic tools, animal breeding methods, functional genomics or genome editing.
To learn more about the research of the aquaculture genetics group at the Roslin Institute, please visit https://www.ed.ac.uk/roslin/aquaculture
Current research interests
Currently one of my main interests is to transfer disease resistance across species. We are currently investigating the genomic basis of resistance to sea lice of Pacific salmon species, with the main aim of transferring it to Atlantic salmon using genome editing. This project involves the use of the latest functional genomic technologies (single-cell sequencing, spatial transcriptomics) and proteomics, and is part of a large international consortium that aims to solve the sea lice problem in Atlantic salmon aquaculture. Other ongoing interests of our research group include exploring disease resistance in shrimp or the role of ubiquitination in response to viral diseases in fish species.-
Evaluation of low-density SNP panels and imputation for cost-effective genomic selection in four aquaculture species
(15 pages)
In:
Frontiers in genetics, vol. 14, pp. 1-16
DOI: https://doi.org/10.3389/fgene.2023.1194266
Research output: Contribution to Journal › Article (E-pub ahead of print) -
A versatile nuclei extraction protocol for single nucleus sequencing in non-model species – optimization in various Atlantic salmon tissues
In:
PLoS ONE
Research output: Contribution to Journal › Article (Accepted/In press) -
A chromosome-level genome assembly enables the identification of the follicule stimulating hormone receptor as the master sex determining gene in the flatfish Solea senegalensis
In:
Molecular Ecology Resources, vol. 23, pp. 886-904
DOI: https://doi.org/10.1111/1755-0998.13750
Research output: Contribution to Journal › Article (Published) -
Understanding host response to infectious salmon anaemia virus in an Atlantic salmon cell line using single-cell RNA sequencing
(12 pages)
In:
BMC Genomics, vol. 161, pp. 1-12
DOI: https://doi.org/10.1186/s12864-023-09254-z
Research output: Contribution to Journal › Article (Published) -
Single cell genomics as a transformative approach for aquaculture research and innovation
(20 pages)
In:
Reviews in Aquaculture, pp. 1-20
DOI: https://doi.org/10.1111/raq.12806
Research output: Contribution to Journal › Review article (E-pub ahead of print)
Organiser
I am involved in the organisation of the Genomics in Aquaculture symposium (https://www.gia2020.es/), a friendly forum for the discussion of everything genomics in aquaculture.