Diego Oyarzún
Reader in Computational Biology

- School of Informatics
- School of Biological Sciences
- SynthSys - Centre for Synthetic & Systems Biology
Contact details
- Email: d.oyarzun@ed.ac.uk
- Web: Biomolecular Control Group
-
Address
- Street
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2.47A, Informatics Forum
10 Crichton St - City
- Edinburgh
- Post code
- EH8 9AB
Background
Diego leads the Biomolecular Control Group at the University of Edinburgh. He holds a joint appointment at the School of Informatics and the School of Biological Sciences. Previously he was a Research Fellow in Biomathematics at Imperial College and a Marie Curie Fellow at INRIA Sophia Antipolis. He did his PhD at the Hamilton Institute in Maynooth University, Ireland. He is originally from Valdivia in southern Chile.
In 2016 Diego was appointed Global Future Council Fellow by the World Economic Forum and in 2017 he was selected as one of the 100 Young Global Changers by the Think 20 Summit, mandated by the G20 presidency. Diego also serves in the Scientific Advisory Board for the WEF Center for the Fourth Industrial Revolution in San Francisco and the EPSRC Early Career Forum in Mathematical Sciences. He is an Associate Editor for the journals Frontiers in Synthetic Biology and Microbial Cell Factories.
More information on the group website:
http://homepages.inf.ed.ac.uk/doyarzun/
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Prediction of Cellular Burden with Host--Circuit Models
(25 pages)
DOI: https://doi.org/10.1007/978-1-0716-1032-9_13
Research output: › Chapter (Published) -
Computation of Single-Cell Metabolite Distributions Using Mixture Models
(11 pages)
In:
Frontiers in Cell and Developmental Biology, vol. 8
DOI: https://doi.org/10.3389/fcell.2020.614832
Research output: Contribution to Journal › Article (Published) -
A stochastic model of gene expression with polymerase recruitment and pause release
(15 pages)
In:
Biophysical Journal
DOI: https://doi.org/10.1016/j.bpj.2020.07.020
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Metabolite sequestration enables rapid recovery from fatty acid depletion in Escherichia coli
In:
mBio, vol. 11
DOI: https://doi.org/10.1128/mBio.03112-19
Research output: Contribution to Journal › Article (Published) -
Multiobjective optimization of gene circuits for metabolic engineering
(4 pages)
In:
IFAC-PapersOnLine, vol. 52, pp. 13-16
DOI: https://doi.org/10.1016/j.ifacol.2019.12.229
Research output: Contribution to Journal › Article (Published) -
Pathways to cellular supremacy in biocomputing
(11 pages)
In:
Nature Communications, vol. 10
DOI: https://doi.org/10.1038/s41467-019-13232-z
Research output: Contribution to Journal › Article (Published) -
Riboswitch identification using Ligase-Assisted Selection for the Enrichment of Responsive Ribozymes (LigASERR)
In:
Synthetic Biology
DOI: https://doi.org/10.1093/synbio/ysz019
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Growth defects and loss-of-function in synthetic gene circuits
(10 pages)
In:
ACS Synthetic Biology, vol. 8, pp. 1231−1240
DOI: https://doi.org/10.1021/acssynbio.8b00531
Research output: Contribution to Journal › Article (Published) -
Stochastic modelling reveals mechanisms of metabolic heterogeneity
(9 pages)
In:
Communications biology, vol. 2
DOI: https://doi.org/10.1038/s42003-019-0347-0
Research output: Contribution to Journal › Article (Published) -
Analysis of a genetic-metabolic oscillator with piecewise linear models
(11 pages)
In:
Journal of Theoretical Biology, vol. 462, pp. 259-269
DOI: https://doi.org/10.1016/j.jtbi.2018.10.026
Research output: Contribution to Journal › Article (Published)