Deborah Charlesworth
Contact details
- Tel: +44 (0)131 650 5751
- Email: deborah.charlesworth@ed.ac.uk
Address
- Street
-
Institute of Evolutionary Biology, University of Edinburgh,
Ashworth Lab., room G.61A - City
- Charlotte Auerbach Road, King's Buildings, Edinburgh
- Post code
- EH9 3FL
Background
1968 PhD (Genetics) Cambridge University
1968 - 69 MRC Junior Research Fellow, Cambridge University
1969-71 Postdoctoral fellow, University of Chicago
1971-74 Honorary Research Fellow, Liverpool University
1974-84 Temporary Lecturer, University of Sussex
1977-78 Visiting Scientist, NIEHS (NIH) North Carolina
1984-88 Research Associate, University of Chicago
1988-92 Assistant Professor, University of Chicago
1992-1997 Professor, University of Chicago
1997-2002 NERC Senior Research Fellow, University of Edinburgh
1997-present Professorial Research Fellow, University of Edinburgh
2005 Fellow of the Royal Society
Open to PhD supervision enquiries?
No
Research summary
Evolutionary and population genetics, particularly topics in the general area of the evolution of breeding systems and sex chromosomes.
Current research interests
The genetics and evolution of the Y chromosome in the guppy (a fish, Poecilia reticulata).Past research interests
Self-incompatibility, the evolution of Y-linked genes in the white campion, Silene latifolia.Research activities
- Genetics (Journal) to Publication peer-review and editorial work types › Editorial activity
- Edinburgh International Science Festival Participating in or organising an event types › Public Engagement – Public lecture/debate/seminar
- Teacher in CUSO workshop for graduate students and post-docs: Evolution of sex-determination mechanisms, La Sage, Switzerland, 17-20 June 2009, CUSO workshop Other activity types › Types of External academic engagement - Research and Teaching at External Organisation
- Ecole Normale Superieure to Visiting an external institution types › Research and Teaching at External Organisation
- Munich Graduate School for Evolution, Ecology, and Systematics Visiting an external institution types › Research and Teaching at External Organisation
- BBSRC summer school on Molecular Evolution and Diversity, BBSRC Summer School in Molecular Evolution and Variation to Other activity types › Types of External academic engagement - Research and Teaching at External Organisation
- Nature (Journal) Publication peer-review and editorial work types › Publication peer-review
- PLoS Biology (Journal) Publication peer-review and editorial work types › Publication peer-review
- PLoS.Genet. (Journal) Publication peer-review and editorial work types › Publication peer-review
- Current Biology (Journal) Publication peer-review and editorial work types › Publication peer-review
- Evolution (Journal) Publication peer-review and editorial work types › Publication peer-review
- BMC Genetics (Journal) Publication peer-review and editorial work types › Editorial activity
- Genetics (Journal) Publication peer-review and editorial work types › Editorial activity
Current project grants
ERC Advanced grant: Evolutionary genetics of guppy sex chromosomes (695225)
Past project grants
NOT LISTED
-
Young sex chromosomes in plants and animals
In:
New Phytologist
DOI: https://doi.org/10.1111/nph.16002
Contribution to journal › Review article (E-pub ahead of print) -
Reply to Wright et al. : How to explain the absence of extensive Y-specific regions in the guppy sex chromosomes
(2 pages)
In:
Proceedings of the National Academy of Sciences, vol. 116, no. 26, pp. 12609-12610
Contribution to journal › Comment/debate (Published) -
Arms races with mitochondrial genome soft sweeps in a gynodioecious plant, Plantago lanceolata
In:
Molecular Ecology
DOI: https://doi.org/10.1111/mec.15121
Contribution to journal › Article (E-pub ahead of print) -
Exaggerated heterochiasmy in a fish with sex-linked male coloration polymorphisms
(8 pages)
In:
Proceedings of the National Academy of Sciences, vol. 116, no. 14, pp. 6924-6931
DOI: https://doi.org/doi.org/10.1073/pnas.1818486116
Contribution to journal › Article (Published) -
Evolution of sex determination and heterogamety changes in section Otites of the genus Silene
In:
Scientific Reports, vol. 9, no. 1
DOI: https://doi.org/10.1038/s41598-018-37412-x
Contribution to journal › Article (Published) -
The importance of the Neutral Theory in 1968 and 50 years on : a response to Kern and Hahn 2018
(4 pages)
In:
Evolution, vol. 73, no. 1, pp. 111-114
DOI: https://doi.org/10.1111/evo.13650
Contribution to journal › Comment/debate (Published) -
Has adaptation occurred in males and females since separate sexes evolved in the plant Silene latifolia?
(8 pages)
In:
Proceedings of the Royal Society B-Biological Sciences, vol. 285, no. 1883
DOI: https://doi.org/10.1098/rspb.2017.2824
Contribution to journal › Article (Published) -
The guppy sex chromosome system and the sexually antagonistic polymorphism hypothesis for y chromosome recombination suppression
(18 pages)
In:
Genes, vol. 9, no. 5
DOI: https://doi.org/10.3390/genes9050264
Contribution to journal › Review article (Published) -
Neutral variation in the context of selection
(3 pages)
In:
Molecular Biology and Evolution, vol. 35, no. 6, pp. 1359-1361
DOI: https://doi.org/10.1093/molbev/msy062
Contribution to journal › Review article (E-pub ahead of print) -
Does sexual dimorphism in plants promote sex chromosome evolution?
(8 pages)
In:
Environmental and experimental botany, vol. 146, pp. 5-12
DOI: https://doi.org/10.1016/j.envexpbot.2017.11.005
Contribution to journal › Review article (Published) -
Mogens Westergaard's Contributions to Understanding Sex Chromosomes
(7 pages)
In:
Genetics, vol. 210, no. 4, pp. 1143-1149
DOI: https://doi.org/10.1534/genetics.118.301128
Contribution to journal › Review article (Published) -
The sources of adaptive variation
In:
Proceedings of the Royal Society B-Biological Sciences, vol. 284, no. 1855
DOI: https://doi.org/10.1098/rspb.2016.2864
Contribution to journal › Article (Published) -
Origins of rice cytoplasmic male sterility genes
In:
Cell Research
DOI: https://doi.org/10.1038/cr.2016.158
Contribution to journal › Article (Published) -
Recombination changes at the boundaries of fully and partially sex-linked regions between closely related Silene species pairs
In:
Heredity, vol. 118, pp. 395-403
DOI: https://doi.org/10.1038/hdy.2016.113
Contribution to journal › Article (Published) -
Evolution of sex-biased gene expression in a dioecious plant
In:
Nature Plants, vol. 2
DOI: https://doi.org/10.1038/nplants.2016.168
Contribution to journal › Article (Published) -
Hubby and Lewontin on protein variation in natural populations : When molecular genetics came to the rescue of population genetics
(7 pages)
In:
Genetics, vol. 203, no. 4, pp. 1497-1503
DOI: https://doi.org/10.1534/genetics.115.185975
Contribution to journal › Article (Published) -
Population genetics from 1966 to 2016
In:
Heredity
DOI: https://doi.org/10.1038/hdy.2016.55
Contribution to journal › Article (Published) -
Plant Sex Chromosomes
(27 pages)
In:
Annual Review of Plant Biology, vol. 67, pp. 397-420
DOI: https://doi.org/10.1146/annurev-arplant-043015-111911
Contribution to journal › Article (Published) -
Frequent, Geographically Structured Heteroplasmy in the Mitochondria of a Flowering Plant, Ribwort Plantain (Plantago lanceolata)
In:
Heredity
DOI: https://doi.org/10.1038/hdy.2016.15
Contribution to journal › Article (E-pub ahead of print) -
A new physical mapping approach refines the sex-determining gene positions on the Silene latifolia Y-chromosome
In:
Scientific Reports, vol. 6
DOI: https://doi.org/10.1038/srep18917
Contribution to journal › Article (Published)
Invited speaker
Invited speaker in Crafoord Prize symposium, Stockholm, May 2015
Invited speaker in symposium on sex chromosomes, annual SMBE Conference, Vienna 2015
Invited speaker in “BarrettFest” symposium honouring SCH Barrett, University of Toronto, September 2018
Participant
Population Genetics Group annual meeting (every year)