Deborah Charlesworth

Contact details
- Tel: +44 (0)131 650 5751
- Email: deborah.charlesworth@ed.ac.uk
Address
- Street
-
Institute of Evolutionary Biology, University of Edinburgh,
Ashworth Lab., room G.61A - City
- Charlotte Auerbach Road, King's Buildings, Edinburgh
- Post code
- EH9 3FL
Background
1968 PhD (Genetics) Cambridge University
1968 - 69 MRC Junior Research Fellow, Cambridge University
1969-71 Postdoctoral fellow, University of Chicago
1971-74 Honorary Research Fellow, Liverpool University
1974-84 Temporary Lecturer, University of Sussex
1977-78 Visiting Scientist, NIEHS (NIH) North Carolina
1984-88 Research Associate, University of Chicago
1988-92 Assistant Professor, University of Chicago
1992-1997 Professor, University of Chicago
1997-2002 NERC Senior Research Fellow, University of Edinburgh
1997-present Professorial Research Fellow, University of Edinburgh
2005 Fellow of the Royal Society
Open to PhD supervision enquiries?
No
Research summary
Evolutionary and population genetics, particularly topics in the general area of the evolution of breeding systems and sex chromosomes.
Current research interests
The genetics and evolution of the Y chromosome in the guppy (a fish, Poecilia reticulata).Past research interests
Self-incompatibility, the evolution of Y-linked genes in the white campion, Silene latifolia.Research activities
- Genetics (Journal) to
- Edinburgh International Science Festival
- Conférence Universitaire de Suisse Occidentale
- Munich Graduate School for Evolution, Ecology, and Systematics
- Ecole Normale Superieure to
- BBSRC summer school on Molecular Evolution and Diversity to
- BMC Genetics (Journal)
- Evolution (Journal)
- Current Biology (Journal)
- PLoS.Genet. (Journal)
- PLoS Biology (Journal)
- Nature (Journal)
- Genetics (Journal)
Current project grants
ERC Advanced grant: Evolutionary genetics of guppy sex chromosomes (695225)
Past project grants
NOT LISTED
-
Chromosome‐scale assembly of the genome of Salix dunnii reveals a male‐heterogametic sex determination system on chromosome 7
(45 pages)
In:
Molecular Ecology Resources
DOI: https://doi.org/10.1111/1755-0998.13362
Research output: Contribution to Journal › Article (Published) -
When and how do sex-linked regions become sex chromosomes?
In:
Evolution
Research output: Contribution to Journal › Article (Accepted/In press) -
Evidences for a role of two Y-specific genes in sex determination in Populus deltoides
In:
Nature Communications, vol. 11
DOI: https://doi.org/10.1038/s41467-020-19559-2
Research output: Contribution to Journal › Article (Published) -
Improved reference genome uncovers novel sex-linked regions in the Guppy (Poecilia reticulata)
(17 pages)
In:
Genome Biology and Evolution, vol. 12, pp. 1789-1805
DOI: https://doi.org/10.1093/gbe/evaa187
Research output: Contribution to Journal › Article (Published) -
The timing of genetic degeneration of sex chromosomes
In:
Philosophical Transactions of the Royal Society B: Biological Sciences
Research output: Contribution to Journal › Article (Accepted/In press) -
Young sex chromosomes in plants and animals
In:
New Phytologist, vol. 224
DOI: https://doi.org/10.1111/nph.16002
Research output: Contribution to Journal › Review article (E-pub ahead of print) -
Reply to Wright et al.: How to explain the absence of extensive Y-specific regions in the guppy sex chromosomes
(2 pages)
In:
Proceedings of the National Academy of Sciences, vol. 116, pp. 12609-12610
Research output: Contribution to Journal › Comment/debate (Published) -
Arms races with mitochondrial genome soft sweeps in a gynodioecious plant, Plantago lanceolata
In:
Molecular Ecology
DOI: https://doi.org/10.1111/mec.15121
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Exaggerated heterochiasmy in a fish with sex-linked male coloration polymorphisms
(8 pages)
In:
Proceedings of the National Academy of Sciences, vol. 116, pp. 6924–6931
DOI: https://doi.org/10.1073/pnas.1818486116
Research output: Contribution to Journal › Article (Published) -
Evolution of sex determination and heterogamety changes in section Otites of the genus Silene
In:
Scientific Reports, vol. 9
DOI: https://doi.org/10.1038/s41598-018-37412-x
Research output: Contribution to Journal › Article (Published) -
The importance of the Neutral Theory in 1968 and 50 years on: a response to Kern and Hahn 2018
(4 pages)
In:
Evolution, vol. 73, pp. 111-114
DOI: https://doi.org/10.1111/evo.13650
Research output: Contribution to Journal › Comment/debate (Published) -
Mogens Westergaard's Contributions to Understanding Sex Chromosomes
(7 pages)
In:
Genetics, vol. 210, pp. 1143-1149
DOI: https://doi.org/10.1534/genetics.118.301128
Research output: Contribution to Journal › Review article (Published) -
Has adaptation occurred in males and females since separate sexes evolved in the plant Silene latifolia?
(8 pages)
In:
Proceedings of the Royal Society B-Biological Sciences, vol. 285
DOI: https://doi.org/10.1098/rspb.2017.2824
Research output: Contribution to Journal › Article (Published) -
The guppy sex chromosome system and the sexually antagonistic polymorphism hypothesis for y chromosome recombination suppression
(18 pages)
In:
Genes, vol. 9
DOI: https://doi.org/10.3390/genes9050264
Research output: Contribution to Journal › Review article (Published) -
Neutral variation in the context of selection
(3 pages)
In:
Molecular Biology and Evolution, vol. 35, pp. 1359-1361
DOI: https://doi.org/10.1093/molbev/msy062
Research output: Contribution to Journal › Review article (E-pub ahead of print) -
Does sexual dimorphism in plants promote sex chromosome evolution?
(8 pages)
In:
Environmental and experimental botany, vol. 146, pp. 5-12
DOI: https://doi.org/10.1016/j.envexpbot.2017.11.005
Research output: Contribution to Journal › Review article (Published) -
The sources of adaptive variation
In:
Proceedings of the Royal Society B-Biological Sciences, vol. 284
DOI: https://doi.org/10.1098/rspb.2016.2864
Research output: Contribution to Journal › Article (Published) -
Origins of rice cytoplasmic male sterility genes
In:
Cell Research
DOI: https://doi.org/10.1038/cr.2016.158
Research output: Contribution to Journal › Article (Published) -
Recombination changes at the boundaries of fully and partially sex-linked regions between closely related Silene species pairs
In:
Heredity, vol. 118, pp. 395-403
DOI: https://doi.org/10.1038/hdy.2016.113
Research output: Contribution to Journal › Article (Published) -
Evolution of sex-biased gene expression in a dioecious plant
In:
Nature Plants, vol. 2
DOI: https://doi.org/10.1038/nplants.2016.168
Research output: Contribution to Journal › Article (Published)
Invited speaker
Invited speaker in Crafoord Prize symposium, Stockholm, May 2015
Invited speaker in symposium on sex chromosomes, annual SMBE Conference, Vienna 2015
Invited speaker in “BarrettFest” symposium honouring SCH Barrett, University of Toronto, September 2018
Participant
Population Genetics Group annual meeting (every year)