Dr David Wragg
Research Fellow
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Background
I was awarded a PhD in Genetics from the University of Nottingham in 2013 where I researched the genetics of blue eggs in chicken. Following on from this I undertook a post-doc position at the Institut National de la Recherche Agronomique in Toulouse, leading the bioinformatic analyses to characterise the genetics diversity of hundreds of honey bee genomes. I joined the Roslin Institute in 2016, embedded within the Centre for Tropical Livestock Genetics and Health (CTLGH), where the focus of my research involved mapping a genetic locus underpinning tolerance to Theileria parva in Boran cattle. Presently I am working on the development of novel omics-based methods to support clinical diagnoses in companion animals. In addition to my research at the University, I am one of the founding directors of the community interest company Beebytes Analytics, which provides honey bee genetics testing and support to the beekeeping community.
Qualifications
- PhD in Genetics (2013), University of Nottingham
- BSc(Hons) Animal Science 1st class (2008), Nottingham Trent University
- HND Computer Studies (2000), Nottingham Trent University
Research summary
My main research interests are:
- the identification of genetic markers for disease tolerance/susceptibility
- developing biomarkers to support clinical diagnosis in animals
- the development of assays to support clinical diagnoses and selective breeding
-
Longitudinal transcriptome analysis of cattle infected with Theileria parva
In:
Int J Parasitol
Research output: Contribution to Journal › Article (Accepted/In press) -
Complex population structure and haplotype patterns in the Western European honey bee from sequencing a large panel of haploid drones: Sequencing haploid honey bee drones
In:
Molecular Ecology Resources
DOI: https://doi.org/10.1111/1755-0998.13665
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Author Correction: A cattle graph genome incorporating global breed diversity
In:
Nature Communications, vol. 13
DOI: https://doi.org/10.1038/s41467-022-30372-x
Research output: Contribution to Journal › Article (Published) -
A locus conferring tolerance to Theileria infection in African cattle
In:
PLoS Genetics
Research output: Contribution to Journal › Article (Accepted/In press) -
A cattle graph genome incorporating global breed diversity
In:
Nature Communications
Research output: Contribution to Journal › Article (Accepted/In press) -
Gene expression patterns observed from the skin of selected cattle breeds infested with Amblyomma hebraeum ticks
Research output: Contribution to Conference › Poster (E-pub ahead of print) -
Gene expression patterns observed from the skin of selected cattle breeds infested with Amblyomma hebraeum ticks
Research output: Contribution to Conference › Abstract (E-pub ahead of print) -
Inherited tolerance in cattle to the apicomplexan protozoan Theileria parva is associated with decreased proliferation of parasite-infected lymphocytes
In:
Frontiers in Cellular and Infection Microbiology
DOI: https://doi.org/10.3389/fcimb.2021.751671
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Clinical evaluation of Corridor disease in Bos indicus (Boran) cattle naturally infected with buffalo-derived Theileria parva
In:
Frontiers in Veterinary Science, vol. 8
DOI: https://doi.org/10.3389/fvets.2021.731238
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Whole-genome sequence data suggests environmental adaptation of Ethiopian sheep populations
In:
Genome Biology and Evolution
DOI: https://doi.org/10.1093/gbe/evab014
Research output: Contribution to Journal › Article (E-pub ahead of print)