Dr David Wragg
Research Fellow
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Background
I was awarded a PhD in Genetics from the University of Nottingham in 2013 where I researched the genetics of blue eggs in chicken. Following on from this I undertook a post-doc position at the Institut National de la Recherche Agronomique in Toulouse, leading the bioinformatic analyses to characterise the genetics diversity of hundreds of honey bee genomes. I joined the Roslin Institute in 2016, embedded within the Centre for Tropical Livestock Genetics and Health (CTLGH), where the focus of my research involved mapping a genetic locus underpinning tolerance to Theileria parva in Boran cattle. Presently I am working on the development of novel omics-based methods to support clinical diagnoses in companion animals. In addition to my research at the University, I am one of the founding directors of the community interest company Beebytes Analytics, which provides honey bee genetics testing and support to the beekeeping community.
Qualifications
- PhD in Genetics (2013), University of Nottingham
- BSc(Hons) Animal Science 1st class (2008), Nottingham Trent University
- HND Computer Studies (2000), Nottingham Trent University
Research summary
My main research interests are:
- the identification of genetic markers for disease tolerance/susceptibility
- developing biomarkers to support clinical diagnosis in animals
- the development of assays to support clinical diagnoses and selective breeding
-
When One’s Not Enough: Colony Pool-Seq Outperforms Individual-Based Methods for Assessing Introgression in Apis mellifera mellifera
(22 pages)
In:
Insects, vol. 5, pp. 1-22
DOI: https://doi.org/10.3390/insects14050421
Research output: Contribution to Journal › Article (E-pub ahead of print) -
AmelHap: Leveraging drone whole-genome sequence data to create a honey bee HapMap
(11 pages)
In:
Scientific Data, vol. 10, pp. 1-11
DOI: https://doi.org/10.1038/s41597-023-02097-z
Research output: Contribution to Journal › Article (Published) -
Signatures of purifying selection and site-specific positive selection on the mitochondrial DNA of dromedary camels (Camelus dromedarius): Purifying and positive selections on camel mtDNA
(7 pages)
In:
Mitochondrion Journal, vol. 69, pp. 36-42
DOI: https://doi.org/10.1016/j.mito.2023.01.004
Research output: Contribution to Journal › Article (Published) -
Longitudinal transcriptome analysis of cattle infected with Theileria parva
In:
International Journal For Parasitology, vol. 52, pp. 799-813
DOI: https://doi.org/10.1016/j.ijpara.2022.07.006
Research output: Contribution to Journal › Article (Published) -
Optical mapping compendium of structural variants across global cattle breeds
(8 pages)
In:
Scientific Data, vol. 9, pp. 1-8
DOI: https://doi.org/10.1038/s41597-022-01684-w
Research output: Contribution to Journal › Article (Published) -
Assessment of genotyping array performance for genome-wide association studies and imputation in African cattle
In:
Genetics Selection Evolution, vol. 54, pp. 1-23
DOI: https://doi.org/10.1186/s12711-022-00751-5
Research output: Contribution to Journal › Article (Published) -
Complex population structure and haplotype patterns in the Western European honey bee from sequencing a large panel of haploid drones: Sequencing haploid honey bee drones
In:
Molecular Ecology Resources, vol. 22, pp. 3068-3086
DOI: https://doi.org/10.1111/1755-0998.13665
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Author Correction: A cattle graph genome incorporating global breed diversity
In:
Nature Communications, vol. 13
DOI: https://doi.org/10.1038/s41467-022-30372-x
Research output: Contribution to Journal › Article (Published) -
A locus conferring tolerance to Theileria infection in African cattle
In:
PLoS Genetics, vol. 18
DOI: https://doi.org/10.1371/journal.pgen.1010099
Research output: Contribution to Journal › Article (Published) -
A cattle graph genome incorporating global breed diversity
In:
Nature Communications, vol. 13
Research output: Contribution to Journal › Article (E-pub ahead of print)