David Newby
Personal Chair - BHF Duke of Edinbugh Chair of Cardiology
Address
- Street
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Chancellor's Building
49 Little France Crescent - City
- Edinburgh
- Post code
- EH16 4SB
Research summary
Professor Newby has major interests in experimental medicine and the advanced imaging of cardiovascular disease including coronary heart disease, aortic stenosis and heart failure. He has held British Heart Foundation Programme Grants exploring the atherothrombotic effects of air pollution, and has interests in the interaction between cardiac and respiratory diseases. He has been involved in several multicentre trials and has played a major role in the conduct of the SALTIRE (Scottish Aortic stenosis Lipid lowering Trial, Impact on REgression) and 3CPO (Health Technology Assessment trial of non-invasive ventilation for acute cardiogenic pulmonary oedema) trials. He currently holds a BHF Programme Grant exploring non-invasive coronary atherothrombosis imaging. He is Chief Investigator for the SCOT-HEART trial funded by the Chief Scientist Office; a national multicentre randomised controlled trial of computed tomography coronary angiography in patients attending the Rapid Access Chest Pain Clinic. He is also Chief Investigator of the National Institute for Health Research Efficacy and Mechanism Evaluation-funded MA3RS study: a multicentre trial of magnetic resonance imaging in abdominal aortic aneurysms. He is Chief Investigator of the Wellcome Trust-funded multicentre trial:Prediction of Recurrent Events with 18F-Fluoride to Identify Ruptured and High-risk Coronary Artery Plaques in Patients with Myocardial Infarction (PRE18FFIR) trial, and the British Heart Foundation funded Dual Antiplatelet Therapy in Acute Coronary Syndromes in Scotland Trial.
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Low shear stress at baseline predicts expansion and aneurysm-related events in patients with abdominal aortic aneurysm
In:
Circulation: Cardiovascular Imaging
Research output: Contribution to Journal › Article (Accepted/In press) -
Prognostic value of fractional flow reserve from computed tomography
In:
Heart
Research output: Contribution to Journal › Editorial (Accepted/In press) -
Lipoprotein(a) is associated with adverse plaque progression
In:
Journal of the American College of Cardiology
Research output: Contribution to Journal › Article (Accepted/In press) -
Major adverse cardiac events in symptomatic women with non-obstructive CAD on coronary CTA: pooled analysis from PROMISE and SCOT-HEART
In:
International Journal of Cardiovascular Imaging
DOI: https://doi.org/10.1007/s10554-021-02429-3
Research output: Contribution to Journal › Article (Published) -
MRI and CT coronary angiography in survivors of COVID-19
In:
Heart, pp. heartjnl-2021-319926
DOI: https://doi.org/10.1136/heartjnl-2021-319926
Research output: Contribution to Journal › Article (Published) -
Early computed tomography coronary angiography in patients with suspected acute coronary syndrome: randomised controlled trial
(12 pages)
In:
British Medical Journal (BMJ), vol. 374
DOI: https://doi.org/10.1136/bmj.n2106
Research output: Contribution to Journal › Article (Published) -
Evaluating Medical Therapy for Calcific Aortic Stenosis: JACC State-of-the-Art Review
In:
Journal of the American College of Cardiology
Research output: Contribution to Journal › Review article (Accepted/In press) -
A novel cardiovascular magnetic resonance risk score for predicting mortality following surgical aortic valve replacement
In:
Scientific Reports
Research output: Contribution to Journal › Article (Accepted/In press) -
Effects of Antiplatelet Therapy After Stroke Caused by Intracerebral Hemorrhage: Extended Follow-up of the RESTART Randomized Clinical Trial
In:
JAMA Neurology
DOI: https://doi.org/10.1001/jamaneurol.2021.2956
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Early CT Coronary Angiography in Patients with Suspected Acute Coronary Syndrome: Randomised Controlled Trial
In:
British Medical Journal (BMJ)
Research output: Contribution to Journal › Article (Accepted/In press) -
Native aortic valve disease progression and bioprosthetic valve degeneration in patients with transcatheter aortic valve implantation
In:
Circulation
Research output: Contribution to Journal › Article (Accepted/In press) -
Categorising myocardial infarction with advanced cardiovascular imaging
In:
The Lancet, vol. 398, pp. e9
DOI: https://doi.org/10.1016/S0140-6736(21)01329-5
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Transcatheter aortic valve replacement for bicuspid aortic stenosis
In:
JAMA Cardiology
Research output: Contribution to Journal › Editorial (Accepted/In press) -
Pericoronary and periaortic adipose tissue density are associated with inflammatory disease activity in Takayasu arteritis and atherosclerosis
In:
European Heart Journal Open
DOI: https://doi.org/10.1093/ehjopen/oeab019
Research output: Contribution to Journal › Article (Published) -
Troponin-Guided Coronary Computed Tomography Angiography After Exclusion of Myocardial Infarction
In:
Journal of the American College of Cardiology
Research output: Contribution to Journal › Article (Accepted/In press) -
In vivo thrombosis imaging in patients recovering from COVID-19 and pulmonary embolism
In:
American Journal of Respiratory and Critical Care Medicine
Research output: Contribution to Journal › Article (Accepted/In press) -
Modelling [18F]LW223 PET data using simplified imaging protocols for quantification of TSPO expression in the rat heart and brain
In:
European Journal of Nuclear Medicine and Molecular Imaging
Research output: Contribution to Journal › Article (Accepted/In press) -
The therapeutic potential of apelin in kidney disease
In:
Nature Reviews Nephrology
Research output: Contribution to Journal › Article (Accepted/In press) -
Association of coronary artery calcium score with qualitatively and quantitatively assessed adverse plaque on coronary CT angiography in the SCOT-HEART trial
In:
European Heart Journal - Cardiovascular Imaging
Research output: Contribution to Journal › Article (Accepted/In press) -
Challenging the obesity paradox: Extreme obesity and COPD mortality in the SUMMIT Trial
In:
ERJ Open Research
DOI: https://doi.org/10.1183/23120541.00902-2020
Research output: Contribution to Journal › Article (E-pub ahead of print)