David Newby
Personal Chair - BHF Duke of Edinburgh Chair of Cardiology

Address
- Street
-
Chancellor's Building
49 Little France Crescent - City
- Edinburgh
- Post code
- EH16 4SB
Research summary
Professor Newby has major interests in experimental medicine and the advanced imaging of cardiovascular disease including coronary heart disease, aortic stenosis and heart failure. He has held British Heart Foundation Programme Grants exploring the atherothrombotic effects of air pollution, and has interests in the interaction between cardiac and respiratory diseases. He has been involved in several multicentre trials and has played a major role in the conduct of the SALTIRE (Scottish Aortic stenosis Lipid lowering Trial, Impact on REgression) and 3CPO (Health Technology Assessment trial of non-invasive ventilation for acute cardiogenic pulmonary oedema) trials. He currently holds a BHF Programme Grant exploring non-invasive coronary atherothrombosis imaging. He is Chief Investigator for the SCOT-HEART trial funded by the Chief Scientist Office; a national multicentre randomised controlled trial of computed tomography coronary angiography in patients attending the Rapid Access Chest Pain Clinic. He is also Chief Investigator of the National Institute for Health Research Efficacy and Mechanism Evaluation-funded MA3RS study: a multicentre trial of magnetic resonance imaging in abdominal aortic aneurysms. He is Chief Investigator of the Wellcome Trust-funded multicentre trial:Prediction of Recurrent Events with 18F-Fluoride to Identify Ruptured and High-risk Coronary Artery Plaques in Patients with Myocardial Infarction (PRE18FFIR) trial, and the British Heart Foundation funded Dual Antiplatelet Therapy in Acute Coronary Syndromes in Scotland Trial.
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Latent Coronary Plaque Morphology From Computed Tomography Angiography, Molecular Disease Activity on Positron Emission Tomography, and Clinical Outcomes
In:
Arteriosclerosis, Thrombosis, and Vascular Biology
DOI: https://doi.org/10.1161/ATVBAHA.123.319332
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Aortic sodium [18 F]fluoride uptake following endovascular aneurysm repair
In:
Heart, pp. heartjnl-2023-322514
DOI: https://doi.org/10.1136/heartjnl-2023-322514
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Impaired myocardial calcium uptake in patients with diabetes mellitus. A manganese-enhanced magnetic resonance imaging study.: Impaired myocardial calcium uptake in diabetes
In:
Journal of the American College of Cardiology
Research output: Contribution to Journal › Article (Accepted/In press) -
Coronary Atherosclerotic Plaque Activity and Future Coronary Events
In:
JAMA Cardiology
Research output: Contribution to Journal › Article (Accepted/In press) -
Symptom onset and the early diagnosis of acute myocardial infarction
In:
European Heart Journal
Research output: Contribution to Journal › Article (Accepted/In press) -
Coronary low-attenuation plaque and high-sensitivity cardiac troponin
In:
Heart, vol. 109, pp. 702-709
DOI: https://doi.org/10.1136/heartjnl-2022-321867
Research output: Contribution to Journal › Article (Published) -
Non‐invasive imaging of functional pancreatic islet beta‐cell mass in people with type 1 diabetes mellitus
In:
Diabetic Medicine
DOI: https://doi.org/10.1111/dme.15111
Research output: Contribution to Journal › Article (Published) -
Artificial intelligence-based Text-to-image Generation of Cardiac CT
In:
Radiology: Cardiothoracic Imaging, vol. 5
DOI: https://doi.org/10.1148/ryct.220297
Research output: Contribution to Journal › Article (Published) -
Contemporary Natural History of Coronary Artery Disease
In:
Annals of Internal Medicine, vol. 176, pp. 574-575
DOI: https://doi.org/10.7326/M23-0533
Research output: Contribution to Journal › Editorial (E-pub ahead of print) -
Artificial intelligence for imaging of vulnerable coronary plaque: making the impossible possible
In:
Nature Reviews Cardiology
Research output: Contribution to Journal › Article (Accepted/In press) -
Role of Computed Tomography Cardiac Angiography in Acute Chest Pain Syndromes
In:
Heart
DOI: https://doi.org/10.1136/heartjnl-2022-321360
Research output: Contribution to Journal › Article (Published) -
Repeatability and Reproducibility of Cardiac Manganese-Enhanced Magnetic Resonance Imaging
In:
Scientific Reports
DOI: https://doi.org/10.1038/s41598-023-29591-z
Research output: Contribution to Journal › Article (Published) -
Clinical quantitative coronary artery stenosis and coronary atherosclerosis imaging
In:
Nature Reviews Cardiology
Research output: Contribution to Journal › Article (Accepted/In press) -
Deep-Learning for Epicardial Adipose Tissue Assessment with Computed Tomography: Implications for Cardiovascular Risk Prediction
In:
JACC: Cardiovascular Imaging
DOI: https://doi.org/10.1016/j.jcmg.2022.11.018
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Deep Learning Estimation of Three-Dimensional Left Atrial Shape from Two-Chamber and Four-Chamber Cardiac Long Axis Views
In:
European Heart Journal - Cardiovascular Imaging
DOI: https://doi.org/10.1093/ehjci/jead010
Research output: Contribution to Journal › Article (Published) -
Impact of patient selection on performance of an early rule-out pathway for myocardial infarction: from research to the real world
In:
Circulation
DOI: https://doi.org/10.1161/CIRCULATIONAHA.122.062419
Research output: Contribution to Journal › Letter (Published) -
Somatostatin Receptor PET/MR Imaging of Inflammation in Patients with Large Vessel Vasculitis and Atherosclerosis
In:
Journal of the American College of Cardiology, vol. 81, pp. 336-354
DOI: https://doi.org/10.1016/j.jacc.2022.10.034
Research output: Contribution to Journal › Article (Published) -
Cost-effectiveness of rapid assessment of potential ischaemic heart disease with CT coronary angiography
In:
Heart
DOI: https://doi.org/10.1136/heartjnl-2022-321211
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Serum Lipoprotein(a) and Bioprosthetic Aortic Valve Degeneration
In:
European Heart Journal - Cardiovascular Imaging
DOI: https://doi.org/10.1093/ehjci/jeac274
Research output: Contribution to Journal › Article (E-pub ahead of print) -
National Trends in Coronary Artery Disease Imaging: Associations With Health Care Outcomes and Costs
In:
JACC: Cardiovascular Imaging
DOI: https://doi.org/10.1016/j.jcmg.2022.10.022
Research output: Contribution to Journal › Article (E-pub ahead of print)