Carmel Moran (PhD FIPEM FIoP)
Personal Chair of Preclinical Ultrasound
- Centre for Cardiovascular Science
Contact details
- Tel: + 44 131 242 6319
- Email: carmel.moran@ed.ac.uk
Address
- Street
-
The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh BioQuarter
- City
- Edinburgh
- Post code
- EH16 4TJ
Research summary
The primary focus of my research is high frequency ultrasound and ultrasonic contrast agents. In 2008, with Wellcome Trust funding (£516K), I established the preclinical ultrasound imaging facility at the University of Edinburgh and have recently been part of a successful application to the Wellcome Trust to establish a preclinical large animal imaging facility. Using ultrasound imaging, we can image adult, neonates and embryonic hearts, livers and kidneys and study their structure and blood flow dynamics in real-time. Additionally using in-house and commerically available ultrasonic contrast agents, we can study the perfusion of organs. In collaboration with NHS colleagues, I am developing novel high resolution test phantoms for performance assessment of preclincial imaging techniques.
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Editorial: Small animal imaging: Technological and methodological advances to improve the translational power
In:
Frontiers in Medicine, vol. 9
DOI: https://doi.org/10.3389/fmed.2022.1099233
Research output: Contribution to Journal › Editorial (Published) -
Community Survey Results Show that Standardisation of Preclinical Imaging Techniques Remains a Challenge
In:
Molecular Imaging and Biology
DOI: https://doi.org/10.1007/s11307-022-01790-6
Research output: Contribution to Journal › Article (Published) -
Best Practice Recommendations for the Safe use of Lung Ultrasound
In:
European Journal of Ultrasound
DOI: https://doi.org/10.1055/a-1978-5575
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Ultrastable shelled PFC nanobubbles: a platform for ultrasound-assisted diagnostics and therapy
In:
Nanomedicine: Nanotechnology, Biology and Medicine
DOI: https://doi.org/10.1016/j.nano.2022.102611
Research output: Contribution to Journal › Article (E-pub ahead of print) -
A Comparison of the Sensitivity of Contrast-Specific Imaging Modes on Clinical and Preclinical Ultrasound Scanners
In:
Tomography, vol. 8, pp. 2285-2297
DOI: https://doi.org/10.3390/tomography8050191
Research output: Contribution to Journal › Article (Published) -
The Imaging Performance of Preclinical Ultrasound Scanners using the Edinburgh Pipe Phantom
In:
Frontiers in Physics
DOI: https://doi.org/10.3389/fphy.2022.802588
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Modelling of magnetic microbubbles to evaluate contrast enhanced magneto-motive ultrasound in lymph nodes – a pre-clinical study
In:
British Journal of Radiology
DOI: https://doi.org/10.1259/bjr.20211128
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Sonoporation of human renal proximal tubular epithelial cells in vitro to enhance the liberation of intracellular miRNA biomarkers.
In:
Ultrasound in Medicine and Biology (UMB)
DOI: https://doi.org/10.1016/j.ultrasmedbio.2022.01.019
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Development of Preclinical Ultrasound Imaging Techniques to Identify and Image Sentinel Lymph Nodes in a Cancerous Animal Model
In:
Cancers, vol. 14, pp. 561
DOI: https://doi.org/10.3390/cancers14030561
Research output: Contribution to Journal › Article (Published) -
Safety aspects of perinatal ultrasound
In:
European Journal of Ultrasound
DOI: https://doi.org/10.1055/a-1538-6295
Research output: Contribution to Journal › Article (Published) -
A novel elastography phantom prototype for assessment of ultrasound elastography imaging performance
In:
Ultrasound in Medicine and Biology (UMB)
DOI: https://doi.org/10.1016/j.ultrasmedbio.2021.05.015
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Tri-modal imaging of gold-dotted magnetic nanoparticles (Au*MNPs) for magnetic resonance imaging (MRI), computerised tomography (CT) and intravascular ultrasound (IVUS): an in vitro study
In:
Nanomedicine
DOI: https://doi.org/10.2217/nnm-2020-0236
Research output: Contribution to Journal › Article (E-pub ahead of print) -
The Imaging Performance of Diagnostic Ultrasound Scanners Using the Edinburgh Pipe Phantom to Measure the Resolution Integral – 15 Years of Experience
In:
European Journal of Ultrasound
DOI: https://doi.org/10.1055/a-1194-3818
Research output: Contribution to Journal › Article (Published) -
Preclinical Ultrasound Imaging - a review of techniques and imaging applications
In:
Frontiers in Physics
DOI: https://doi.org/10.3389/fphy.2020.00124
Research output: Contribution to Journal › Review article (Published) -
Endothelin-1 mediates the systemic and renal hemodynamic effects of GPR81 activation
In:
Hypertension
DOI: https://doi.org/10.1161/HYPERTENSIONAHA.119.14308
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Electrocardiogram-gated Kilohertz Visualisation (EKV) Ultrasound Allows Assessment of Neonatal Cardiac Structural and Functional Maturation and Longitudinal Evaluation of Regeneration After Injury
In:
Ultrasound in Medicine and Biology (UMB)
DOI: https://doi.org/10.1016/j.ultrasmedbio.2019.09.012
Research output: Contribution to Journal › Article (E-pub ahead of print) -
EFSUMB Clinical Safety Statement for Diagnostic Ultrasound
In:
European Journal of Ultrasound
DOI: https://doi.org/10.1055/a-1010-6018
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Contrast-enhanced magnetomotive ultrasound imaging (CE-MMUS) for colorectal cancer staging: Assessment of sensitivity and resolution to detect alterations in tissue stiffness
(4 pages)
DOI: https://doi.org/10.1109/ULTSYM.2019.8926058
Research output: Contribution to Conference › Conference contribution (Published) -
3D angle-independent Doppler and speckle tracking for the myocardium and blood flow
In:
Echo research and practice
DOI: https://doi.org/10.1530/ERP-19-0040
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Probing Phospholipid Microbubbles by Atomic Force Microscopy to Quantify Bubble Mechanics and Nanostructural Shell Properties
(10 pages)
In:
Colloids and Surfaces B: Biointerfaces, vol. 181, pp. 506-515
DOI: https://doi.org/10.1016/j.colsurfb.2019.04.062
Research output: Contribution to Journal › Article (Published)