Bruce Guthrie (FRSE FMedSci)

Professor of General Practice


I am Professor of General Practice at the University of Edinburgh where I carry out applied research to translate basic and clinical research into effective and reliable clinical practice. I work clinically as a GP at Mackenzie Medical Centre in Edinburgh. I was previously a Medical Research Council Health Services Research Fellow at University of Edinburgh, an National Institute for Health Research post-doctoral research fellow at University of Dundee, a 2006/7 Commonwealth Fund Harkness Fellow in Healthcare Policy at University of California San Francisco where I was also a Visiting Professor in 2010, and Professor of Primary Care Medicine at University of Dundee. I am a member of several grant panels (currently Wellcome and MRC), contribute to undergraduate and postgraduate medical teaching, and supervise and examine MSc and PhD students in Edinburgh and other universities. As well as conducting research, I serve or have served on a number of National Health Service advisory bodies, including the National Institute for Health and Clinical Excellence (NICE) Quality and Outcomes Framework Indicators Advisory Committee (which recommended which quality indicators should be included in the UK primary care pay for performance programme) where I chaired the Thresholds, Review and Retiral Sub-committee, and the Scottish Government Polypharmacy Working Group. I was the chair of the guideline development group of the NICE Multimorbidity Clinical Guideline published in late 2016. 

Open to PhD supervision enquiries?


Research summary

My main research interests are the quality and safety of healthcare, particularly in primary care and currently focused on prescribing quality and safety, multimorbidity the organisation of healthcare. I am a mixed methods researcher and collaborate with researchers from a wide range of disciplines and institutions. The methods I use include quantitative analysis of large, routine datasets; cluster randomised trials with mixed methods parallel process evaluations; and qualitative analysis of interview and observational data. My recent and current work includes development and evaluation of interventions to improve polypharmacy, examination of the implications of competing mortality risk for single disease risk prediction, and examination of the applicability of trial evidence to clinical populations. I am a member of the Primary Care and Multimorbidity Research Group and Director of the Advanced Care Research Centre.

Affiliated research centres