Dr. Appie Beqqali | The University of Edinburgh

Research Fellow

Centre for Cardiovascular Science

Email: A.Beqqali@ed.ac.uk

Publications

Human embryonic stem cell-derived endothelial cell product injection attenuates cardiac remodeling in myocardial infarction 10 Oct 2022 In: Frontiers in Cardiovascular Medicine
DOI: https://doi.org/10.3389/fcvm.2022.953211
Research output: Contribution to Journal › Article (Published)
Mapping the developing human cardiac endothelium at single cell resolution identifies MECOM as a regulator of arteriovenous gene expression 25 Feb 2022 In: Cardiovascular Research
DOI: https://doi.org/10.1093/cvr/cvac023
Research output: Contribution to Journal › Article (Published)
Human AdV-20-42-42, a promising novel adenoviral vector for gene therapy and vaccine product development 1 Sep 2021 In: Journal of Virology
DOI: https://doi.org/10.1128/JVI.00387-21
Research output: Contribution to Journal › Article (E-pub ahead of print)
Extracellular Vesicle miRNAs in the Promotion of Cardiac Neovascularisation 25 Sep 2020 In: Frontiers in physiology
DOI: https://doi.org/10.3389/fphys.2020.579892
Research output: Contribution to Journal › Review article (E-pub ahead of print)
RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling 25 Sep 2018 In: Circulation, vol. 138, pp. 1330–1342
DOI: https://doi.org/10.1161/CIRCULATIONAHA.117.031947
Research output: Contribution to Journal › Article (Published)
The MEF2 transcriptional target DMPK induces loss of sarcomere structure and cardiomyopathy Sep 2018 In: Cardiovascular Research, vol. 114
DOI: https://doi.org/10.1093/cvr/cvy091
Research output: Contribution to Journal › Article (Published)
Alternative splicing in cardiomyopathy 26 Jul 2018 In: Biophysical Reviews
DOI: https://doi.org/10.1007/s12551-018-0439-y
Research output: Contribution to Journal › Review article (Published)
The clinical outcome of LMNA missense mutations appears to be associated with the amount of mutated protein in the nuclear envelope 26 Jun 2018 In: European Journal of Heart Failure
DOI: https://doi.org/10.1002/ejhf.1241
Research output: Contribution to Journal › Article (Published)
Cardiac circRNAs Arise Mainly From Constitutive Exons Rather Than Alternatively Spliced Exons 22 Mar 2018 In: RNA
DOI: https://doi.org/10.1261/rna.064394.117
Research output: Contribution to Journal › Article (E-pub ahead of print)
Z-disc protein CHAPb induces cardiomyopathy and contractile dysfunction in the postnatal heart 5 Dec 2017 In: PLoS ONE, vol. 12, pp. e0189139
DOI: https://doi.org/10.1371/journal.pone.0189139
Research output: Contribution to Journal › Article (Published)
The RNA-binding protein Rbm38 is dispensable during pressure overload-induced cardiac remodeling in mice 29 Aug 2017 In: PLoS ONE, vol. 12, pp. e0184093
DOI: https://doi.org/10.1371/journal.pone.0184093
Research output: Contribution to Journal › Article (Published)
TECRL, a new life‐threatening inherited arrhythmia gene associated with overlapping clinical features of both LQTS and CPVT (19 pages) 1 Dec 2016 In: EMBO Molecular Medicine, vol. 8, pp. 1390-1408
DOI: https://doi.org/10.15252/emmm.201505719
Research output: Contribution to Journal › Article (Published)
RBM20 Regulates Circular RNA Production From the Titin Gene (8 pages) 14 Oct 2016 In: Circulation Research, vol. 119, pp. 996-1003
DOI: https://doi.org/10.1161/CIRCRESAHA.116.309568
Research output: Contribution to Journal › Article (Published)
A mutation in the glutamate-rich region of RNA-binding motif protein 20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank–Starling mechanism (12 pages) Oct 2016 In: Cardiovascular Research, vol. 112, pp. 452-463
DOI: https://doi.org/10.1093/cvr/cvw192
Research output: Contribution to Journal › Article (Published)
A targeted metabolomics assay for cardiac metabolism and demonstration using a mouse model of dilated cardiomyopathy 14 Apr 2016 In: Metabolomics : Official journal of the Metabolomic Society, vol. 12, pp. 59
DOI: https://doi.org/10.1007/s11306-016-0956-2
Research output: Contribution to Journal › Article (Published)
Long Non-Coding RNA Malat-1 Is Dispensable during Pressure Overload-Induced Cardiac Remodeling and Failure in Mice 26 Feb 2016 In: PLoS ONE, vol. 11, pp. e0150236
DOI: https://doi.org/10.1371/journal.pone.0150236
Research output: Contribution to Journal › Article (Published)
Insights into alternative splicing of sarcomeric genes in the heart (7 pages) Apr 2015 In: Journal of Molecular and Cellular Cardiology, vol. 81, pp. 107-13
DOI: https://doi.org/10.1016/j.yjmcc.2015.02.008
Research output: Contribution to Journal › Article (Published)
The LMNA mutation p.Arg321Ter associated with dilated cardiomyopathy leads to reduced expression and a skewed ratio of lamin A and lamin C proteins (10 pages) 15 Nov 2013 In: Experimental Cell Research, vol. 319, pp. 3010-9
DOI: https://doi.org/10.1016/j.yexcr.2013.08.024
Research output: Contribution to Journal › Article (Published)
Sarcosin (Krp1) in skeletal muscle differentiation: gene expression profiling and knockdown experiments (9 pages) 23 Apr 2012 In: The International Journal of Developmental Biology, vol. 56, pp. 301-9
DOI: https://doi.org/10.1387/ijdb.113327lp
Research output: Contribution to Journal › Article (Published)
Cytoskeletal heart-enriched actin-associated protein (CHAP) is expressed in striated and smooth muscle cells in chick and mouse during embryonic and adult stages (7 pages) 2 Sep 2011 In: The International Journal of Developmental Biology, vol. 55, pp. 649-55
DOI: https://doi.org/10.1387/ijdb.103207wv
Research output: Contribution to Journal › Article (Published)

View all 24 publications on Research Explorer

This article was published on 15 Apr, 2024