Andrew Sims

Senior Research Fellow - Bioinformatics


Following graduation from the University of Edinburgh with a BSc.(Hon) in Biological Sciences, Andy worked as a Research Assistant at the British Antarctic Survey laboratories in Cambridge, characterizing the biodiversity of soil samples. He then worked as a Clinical Scientist at the Public Health Laboratories at Addenbrooke’s Hospital (Cambridge), developing real-time quantitative methods for routine viral diagnostics.

Andy then moved to Prof. Steve Oliver’s lab at the University of Manchester to study for his PhD, performing some of the first microarray experiments and comparative genomics analysis at an exciting time when whole-genome sequences of several species of filamentous fungi were completed. Six months of his studies were spent at a US biotech company in California (Genencor) studying the secretory pathway and identifying novel proteases.

Dr Sims continued his focus on gene expression profiling whilst developing his interest in Breast Cancer during subsequent postdoctoral research with Prof. Tony Howell at the Paterson Institute for Cancer Research at the Christie Hospital in Manchester. He conducted a range of translational gene expression profiling projects looking at how known risk factors and preventative interventions for breast cancer actually impart their effects on patients.

In June 2008, Andy relocated to the University of Edinburgh Cancer Research Centre to establish his own research group and provide bioinformatics input to ongoing collaborative multidisciplinary projects. His research interests cover a broad spectrum, but could be summed up simply as ‘trying to make sense of lots of data, to improve our understanding of cancer’. In 2013, Andy was promoted to a tenured Senior Research Fellow.

Responsibilities & affiliations

Director of Taught Education and Learning at the IGMM

Fellow of the Higher Education Academy



Undergraduate teaching

In January 2019 I was appointed Director of Taught Education and Learning at the IGMM with the remit to enhance and develop teaching from the Insitute.

Leveraging our world class research to deliver inspiring lectures and sought after practical skills.

I am co-Course organiser for the Reproductive Cancers UG elective course and teach on the Cancer Biology and Medicine elective course


Postgraduate teaching

I teach precision oncology on the Biomedical Sciences MSc

Open to PhD supervision enquiries?


Current PhD students supervised

Katie Roome - MSc student

Karina Tristán Moreno - MSc student

Yana Chen - MSc student

Guler Gul - PhD student

Nick Moir (with Ian simpson) PhD student

Laura Gomez Cuadrado (with Val Brunton) PhD student

Duniya Mosly (with Simon Langdon) PhD student

Giovanni Tramonti (with Peter Hall) PhD student

Past PhD students supervised

Richard Bownes (with Olga Oikonomidou) PhD

Yanping Xie MSc

Maria Bonello (with Simon Langdon) PhD

Dominic Pearce  (With Mike Dixon) PhD

Ajit Nirmal (with Tom Freeman) PhD

Robb Hollis (with Charlie Gourley) PhD

Victoria Wilson (with Mike Dixon) MD

Laura Arthur (with Mike Dixon) MD

Matina Fragkogianni (with Jeff Pollard) PhD

Anas Saeed (with Victor Lopes) PhD

Arran Turnbull (with Mike Dixon) PhD 

Colette Meyer (with Simon Langdon) PhD

Robert Kitchen PhD

View all 113 publications on Research Explorer