Dr Abigail Diack
Research Operations Manager
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Background
Dr Abigail Diack is an animal scientist with ten years experience in the study of prion diseases or transmissible spongiform encephalopathies (TSE). She completed a BSc in Animal Science at the University of Aberdeen, followed by a MSc in Mammalian Reproduction at the University of Aberdeen/Scottish Agriculture College. She then went onto a PhD at the University of Glasgow studying the genetics of the porcine acute phase proteins.
Dr Diack joined the Roslin Institute in 2007 as a post-doctoral fellow and in 2017 was made a Career Track Fellow. She runs a research group in which the primary research focus is understanding the potential for prion strains to move within and between species and the mechanisms involved. She and her group have expertise in TSE neuropathology, biochemistry and the use of TSE in vivo models.
Qualifications
2004 Doctor of Philosophy (PhD), University of Glasgow Study of the genetics of the porcine acute phase proteins
2003 Master in Science, University of Aberdeen
1999 Bachelor of Science, University of Aberdeen
Research summary
Human and animal prion disease pathogenesis and strain characterisation.
-
Fourth Report on Chicken Genes and Chromosomes 2022
In:
Cytogenetic and Genome Research
DOI: https://doi.org/10.1159/000529376
Research output: Contribution to Journal › Review article (E-pub ahead of print) -
Prions and Diseases: Transgenic Mice Modelling in Prion Diseases
DOI: https://doi.org/10.1007/978-3-031-20565-1_15
Research output: › Chapter (peer-reviewed) (Published) -
The Role of Microglia in CNS Innate Immune Memory
Research output: Contribution to Conference › Poster (Published) -
Identification of a Homology-Independent Linchpin Domain Controlling Mouse and Bank Vole Prion Protein Conversion
In:
PLoS Pathogens
DOI: https://doi.org/10.1371/journal.ppat.1008875
Research output: Contribution to Journal › Article (E-pub ahead of print) -
No adaption of the prion strain in a heterozygous case of variant Creutzfeldt-Jakob disease
(4 pages)
In:
Emerging Infectious Diseases, vol. 26, pp. 1300-1303
DOI: https://doi.org/10.3201/eid2606.191116
Research output: Contribution to Journal › Article (Published) -
Corrigenda : Variant Creutzfeldt-Jakob disease strain is identical in individuals of two PRNP codon 129 genotypes
In:
Brain, vol. 142, pp. e22
DOI: https://doi.org/10.1093/brain/awz129
Research output: Contribution to Journal › Comment/debate (Published) -
Variant Creutzfeldt-Jakob Disease strain is identical in individuals of two PRNP codon 129 genotypes
In:
Brain, vol. 142, pp. 1416-1428
DOI: https://doi.org/10.1093/brain/awz076
Research output: Contribution to Journal › Article (Published) -
Unravelling the glial response in the pathogenesis of Alzheimer's Disease
(12 pages)
In:
The FASEB Journal, vol. 32, pp. 5766-5777
DOI: https://doi.org/10.1096/fj.201801360R
Research output: Contribution to Journal › Review article (Published) -
Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates.
In:
Scientific Reports, vol. 8
DOI: https://doi.org/10.1038/s41598-018-28296-y
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Experimental models of human prion diseases and prion strains
(16 pages)
DOI: https://doi.org/10.1016/B978-0-444-63945-5.00004-0
Research output: › Chapter (peer-reviewed) (E-pub ahead of print)