Dr Riccardo Marioni


I am a University of Edinburgh Chancellor's Fellow based in the Centre for Genomic and Experimental Medicine and the Centre for Cognitive Ageing and Cognitive Epidemiology. 

My fellowship was part-funded by the University of Queensland where I was an Adjunct Research Fellow between 2013-2016.

My postdoctoral research included a year at the Department of Public Health and Primary Care at the University of Cambridge (2009-2010).  Whilst there, I was awarded an Alzheimer's Research UK fellowship (2010-2013) in conjunction with the Medical Research Council Biostatistics Unit, Cambridge, the Department of Biostatistics, INSERM U897, Bordeaux and the University of Edinburgh Department of Psychology, to develop and apply longitudinal statistical methods for cognitive ageing. 


Academic Qualifications

  • Bachelor

    • 2005, Bachelor of Science, University of Aberdeen
  • Master
    • 2006, Master of Science, University of Edinburgh
  • Doctorate
    • 2009, Doctor of Philosophy, PhD, University of Edinburgh

Research summary

My group’s primary research goal is to use computational models to understand the molecular mechanisms that underlie Alzheimer’s disease and to enhance prediction of the disease. We have a passion for research into ageing and, in particular, examining the genetic and environmental contributions to health, cognitive ageing, and dementia. Our work is at the intersection of the biomedical and social sciences.

We work with data from large, population-based cohorts including Generation Scotland, UK Biobank, and the Lothian Birth Cohorts of 1921 and 1936.

Current project grants

Omics prediction of Alzheimer’s disease.
Alzheimer's Research UK Major Project Grant (ARUK-PG2017B-10)
Role: Principal Investigator
Duration: 01/10/17 - 30/09/20
Award: £166,833

A non-invasive mouse DNA methylation age predictor for longitudinal studies.
Centre for Cognitive Ageing and Cognitive Epidemiology Pilot Grant
Role: Principal Investigator
Duration: 01/10/17 - 31/12/18
Award: £5,404

Past project grants

Epigenetic, structural brain MRI, and cognitive changes over the eighth decade.
Gertrude Winifred Gear Fund, University of Edinburgh College of Medicine and Veterinary Medicine & Wellcome Trust - University of Edinburgh Institutional Strategic Support Fund
Role: Principal Investigator
Duration: 03/01/16 - 12/01/16
Award: £108,800

INTERpreting epigenetic signatures in STudies of Early Life Adversity (InterStELA).
ESRC/BBSRC Network Grant (ES/N000382/1)
Role: Co-Investigator, PI: Laura Howe, University of Bristol
Duration: 10/01/2015 - 09/30/17
Award: £199,513

Epigenetics: Environment, Embodiment and Equality (E4).
ESRC/BBSRC Project Grant (ES/N000498/1)
Role: Co-Investigator, PI: Caroline Relton, University of Bristol
Duration: 10/01/2015 - 30/09/18
Award: £667,460

The epiGenetIcs Leads to aGe-relAted diseases (GILGA-mesh) Network.
NIH: U34 Research Grant (AG051425-01)
Role: Co-Investigator, PI: Steve Horvath, UCLA
Duration: 10/01/2015 - 30/09/18
Award: $953,566

View all 174 publications on Research Explorer