Dr Nizar Batada
- Centre for Genomic and Experimental Medicine
- MRC Institute of Genetics and Molecular Medicine
Contact details
- Email: Nizar.Batada@ed.ac.uk
Background
I’m a group leader at the Centre for Genomic and Experimental Medicine (CGEM) within the MRC Institute of Genetics and Molecular Medicine (IGMM), University of Edinburgh. I obtained my Ph.D. in Biophysics from Stanford University and did postdocs at the University of Toronto and Harvard Medical School. My research interests lies in exploiting bulk and single cell genome and transcriptome sequencing of cancer genomes to characterise DNA repair mechanisms that contribute to mutations and study the role of tumour microenvironment in promoting metastasis. I am also interested in developing bioinformatics methods to identify biomarkers that indicate or respond to cancer immunotherapies. I have published - as first or senior author - papers in top tier journals such as Nature, Nature Genetics, PNAS and PLoS Biology.
-
Single-cell analysis uncovers differential regulation of lung γδ T cell subsets by the co-inhibitory molecules, PD-1 and TIM-3
DOI: https://doi.org/10.1101/2021.07.04.451035
Research output: › Other contribution (Published) -
Single-cell RNA sequencing of human breast tumour-infiltrating immune cells reveals a γδ T-cell subtype associated with good clinical outcome
In:
Life Science Alliance, vol. 4, pp. e202000680
DOI: https://doi.org/10.26508/lsa.202000680
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages
In:
Science Immunology, vol. 5
DOI: https://doi.org/10.1126/sciimmunol.abc4466
Research output: Contribution to Journal › Article (Published) -
scID uses discriminant analysis to identify transcriptionally equivalent cell types across single cell RNA-seq data with batch effect
In:
iScience
DOI: https://doi.org/10.1016/j.isci.2020.100914
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells
In:
Genes and Development
DOI: https://doi.org/10.1101/gad.321968.118
Research output: Contribution to Journal › Article (E-pub ahead of print)