MRC Human Genetics Unit
Medical Research Council Human Genetics Unit

Andrew Wood Research Group

Genome Stability and Genome Editing

Dr Andrew Wood - IGC Chancellor's Fellow and Sir Henry Dale Fellow

Section: Genome Regulation

Research in a Nutshell 

In order to maintain a stable genome through cell division, chromosomes must undergo replication and then condense before segregating equally into daughter cells during mitosis.  My laboratory uses blood cell development to understand how effectively these processes operate during the course of normal tissue development and homeostasis, and the consequences of their malfunction on mutagenesis and malignancy.

Several other projects in the lab make use of genome editing technologies. We are using CRISPR/Cas9 to study fundamental mechanisms of DNA repair, and to develop novel genome engineering strategies that expand the genetic toolbox.

Andrew Wood research group 4.2019


Dr Andrew Wood Group Leader
Irene Kallimasioti-Pazi PhD Student
Dr Gillian Taylor Postdoctoral Scientist
Lewis MacDonald PhD Student
Jennifer Brisbane PhD Student



  • Dr Ian Adams
  • Professor Wendy Bickmore
  • Professor Andrew Jackson
  • Professor Colin Semple

Partners and Funders

  • The Wellcome Trust
  • The Royal Society

Scientific Themes

genome stability, mutagenesis, chromosome structure, cell proliferation

Technology Expertise

Genome editing, flow cytometry, in vivo modelling