Chromatin Structure and Genome Integrity
In mammalian cells DNA is wrapped around proteins to form chromatin. This protects DNA from damage and regulates gene transcription. Our lab is studying the protein and epigenetic factors that modify DNA and chromatin structure influencing gene expression and genome stability.
A key goal of our research is to understand how changes in chromatin structure affect gene expression and genome stability in disease. These studies will help us to understand this process and develop future drugs to treat diseases like cancer.
|Professor Nick Gilbert||Group Leader|
|Jim Allan||Honorary Research Fellow|
|Lora Boteva||Research Fellow|
|Peter Bruton||PhD student|
|Adam Buckle||Postdoctoral Scientist|
|Catherine Doust||PhD student|
|Catherine Naughton||Senior Postdoctoral Scientist|
|Ryu-Suke Nozawa||Postdoctoral Scientist|
|Hannah Sutcliffe||PhD student|
|Isobel MacGregor||PhD student|
Chromatin, DNA, Transcription, Genome Stability