Nick Gilbert Research Group
Chromatin Structure and Genome Integrity
Section: Genome Regulation
Research in a Nutshell
In mammalian cells DNA is wrapped around proteins to form chromatin. This protects DNA from damage and regulates gene transcription. Our lab is studying the protein and epigenetic factors that modify DNA and chromatin structure influencing gene expression and genome stability.
A key goal of our research is to understand how changes in chromatin structure affect gene expression and genome stability in disease. These studies will help us to understand this process and develop future drugs to treat diseases like cancer.
People |
|
| Professor Nick Gilbert | Group Leader |
| Jim Allan | Honorary Research Fellow |
| Jamilla Miles | PhD student |
| Adam Buckle | Postdoctoral Scientist |
| Waad Albawardi | PhD student |
| Davide Michieletto | Postdoctoral Scientist |
| Catherine Naughton | Senior Postdoctoral Scientist |
|
Mattia Marenda |
Postdoctoral Scientist |
| Elaine Groat | PhD student |
| Isobel MacGregor | PhD student |
Contact
Collaborations
- Professor Mark Bradley, University of Edinburgh
- Professor Davide Marenduzzo, University of Edinburgh
- Dr Ian Adams, HGU
Partners and Funders
- MRC
Scientific Themes
Chromatin, DNA, Transcription, Genome Stability