Current research SDRNT1BIO
Research using the SDRNT1BIO is aiming to identify those most at risk of complications, and to investigate potential early-warning signs of possible future complications.
The current research projects in 2017-18 are:
- Genome wide single nucleotide polymorphism (SNP) data in a large cohort of people with Type 1 Diabetes (funded by Diabetes UK)
- Characterising the Extremes of Liability to Diabetic Complications (funded by JDRF).
- Validation of Novel and Candidate Biomarkers for Diabetic Kidney Disease in Large Cohorts of people with type 1 diabetes (funded by JDRF).
- Predictors of Early Stage Decline in Kidney Function in Type 1 Diabetes Diabetic Nephropathy Biomarker Discovery and Validation Using Type 1 Diabetes Cohorts (funded by JDRF).
- Epidemiology of Persistent C-Peptide and Its Association with Complications and Other Features in the SDRN Type 1 Bioresource: Potential Mechanisms of Persistence of C-peptide in Established Type 1 Diabetes.
The project work involves a wide number of collaborations, including with:
- Universities: Cambridge, California, Dundee, Exeter, Glasgow, Harvard, King’s College London, Michigan, Pittsburgh, Toronto, Washington, Wisconsin
- Research Centres: Broad Institute, Folkhälsan, Generation Scotland, Genos, Joslin diabetes Center, Steno Diabetes Center
Interested collaborators should contact the Study Co-ordinator in the first instance, email SDRN.T1BIO@ed.ac.uk
Cohort Profile: Scottish Diabetes Research Network Type 1 Bioresource Study (SDRNT1BIO). Published by the International Journal of Epidemiology, October 2016