We seek to understand how DNA changes impact on human health and disease, and how genes and the genome act in normal development and physiology.
Our four research sections enhance collaboration, sharing and mutual feedback on our work. Section meetings are open to all and collaboration between sections is widespread and fruitful.
Our research harnesses the power of large genome-size and population data to reveal the complex nature of disease processes.
Members: Tamir Chandra, Helen Colhoun, Ailith Ewing, Ava Khamseh, Chris Ponting, Colin Semple, Martin Taylor and Catalina Vallejos
Affiliated Members: Sjoerd Beenties, Alison Meynert and Albert Tenesa
Section Head: Professor Chris Ponting
Our research focuses on mechanisms that maintain the stability of the genome between cells and between generations, regulate the expression of genes and how changes to these contribute to disease.
Members: Ian Adams, Wendy Bickmore, Javier Caceres, Tom Deegan, Nick Gilbert, Greg Kudla, Richard Meehan and Duncan Sproul
Section Head: Professor Javier Caceres
Our research aims to understand how changes in our genomes cause disease using clinical data, computational modelling and functional genomic approaches
Members: Oriol Canela-Xandri, Yanick Crow, Andrew Jackson, Hannah Long and Joe Marsh
Section Head: Professor Yanick Crow
Our research employs state of the art cell, organoid and animal models to probe the mechanisms of diseases including developmental disorders and cancer
Members: Luke Boulter, Malcolm Dunlop, Pleasantine Mill, Jenny Nichols, Liz Patton, Veronique Vitart and Andrew Wood.
Section Head: Professor Liz Patton