Edinburgh Drug Discovery

Publications Archive

Our selected publications are archived from 2010 onwards.

Selected articles from 2012

Synthesis of polystyrene microspheres and functionalization with Pd(0) nanoparticles to perform bioorthogonal organometallic chemistry in living cells

A. Unciti-Broceta, E. M. Johansson, R. M. Yusop, R. M. Sanchez-Martin and M. Bradley Nat Protoc (2012):  7(6): 1207-18

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Advancing cancer drug discovery towards more agile development of targeted combination therapies

N. O. Carragher, A. Unciti-Broceta and D. A. Cameron Future Med Chem (2012):  4(1): 87-105

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Combining imaging and pathway profiling: an alternative approach to cancer drug discovery

N. O. Carragher, V. G. Brunton and M. C. Frame Drug Discov Today (2012):  17(5-6): 203-14

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Selected articles from 2011

Live cell in vitro and in vivo imaging applications: accelerating drug discovery

B. Isherwood, P. Timpson, E. J. McGhee, K. I. Anderson, M. Canel, A. Serrels, V. G. Brunton and N. O. Carragher Pharmaceutics (2011):  3(2): 141-70

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Advancing High Content Analysis Towards Improving Clinical Efficacy

N. Carragher European Pharmaceutical Review (2011):  16(1): 12-16

Selected articles from 2010

Modulation of 11beta-hydroxysteroid dehydrogenase type 1 activity by 1,5-substituted 1H-tetrazoles

S. P. Webster, M. Binnie, K. M. McConnell, K. Sooy, P. Ward, M. F. Greaney, A. Vinter, T. D. Pallin, H. J. Dyke, M. I. Gill, I. Warner, J. R. Seckl and B. R. Walker Bioorg Med Chem Lett (2010):  20(11): 3265-71

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Partial deficiency or short-term inhibition of 11beta-hydroxysteroid dehydrogenase type 1 improves cognitive function in aging mice

K. Sooy, S. P. Webster, J. Noble, M. Binnie, B. R. Walker, J. R. Seckl and J. L. Yau J Neurosci (2010):  30(41): 13867-72

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High-content phenotypic profiling of drug response signatures across distinct cancer cells

P. D. Caie, R. E. Walls, A. Ingleston-Orme, S. Daya, T. Houslay, R. Eagle, M. E. Roberts and N. O. Carragher Mol Cancer Ther (2010):  9(6): 1913-26

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