College of Medicine & Veterinary Medicine

Study looks at why chickens overeat

The welfare of poultry could be improved by a discovery about how chickens regulate their appetites.

University scientists have identified how a chicken’s genetic make-up can affect the signals sent from its stomach to its brain that tell a chicken when it has had enough to eat.

Insensitivity to being full

Poultry farmers often have to restrict food for chickens because some birds are insensitive to feelings of fullness and can overeat, affecting their ability to reproduce.

The study could make it easier to develop methods to develop diets that reduce excess growth more naturally in these birds.

The findings shed greater light on food intake in birds and help us understand why some breeds – in general the faster growing types of chickens – are more insensitive to feelings of fullness than others.

Dr Ian DunnThe Roslin Institute

Genetic differences

Researchers say that genetic differences, which affect when chickens recognise when they have had enough to eat, could date back thousands of years when chickens were first domesticated and breeds were selected for their size.

The research was carried out by The Roslin Institute at the University.

Role of protein

Researchers focused on a protein called cholecystokinin.

The protein has a key role in sending signals linked to being full from the gut to the brain.

The researchers found that some birds were better equipped than others at recognising the protein, making them more effective in triggering signals of feeling full.


The study, published in the American Journal of Physiology, Endocrinology and Metabolism, was funded by the Biotechnology and Biological Sciences Research Council.

It involved cross-breeding a fast-growing meat production strain of chicken with a relatively slow-growing, chicken.

The researchers looked at how the protein was processed in both types of chickens and in the new cross breed.

They showed that reduced levels of protein that recognizes the fullness signal also affected the chicken’s natural body weight.

Changes in appetite

Their findings back up the theory that, when poultry were domesticated thousands of years ago and bred for increased size, their appetite levels were changed.

The study could also help inform research looking at appetite regulation in other animals.

All species regulate their appetites to make sure the amount of food taken in is just the right to maintain body weight and fat content. Our research has shown that there is genetic variation in the interpretation of biological signals sent relating to being full. This also affects what would be considered to be the natural body weight of chickens.

Dr Ian DunnThe Roslin Institute