Tissue Repair student Darren Wisniewski contributes to paper on developmental patterning
Darren Wisniewski co-author on paper by Lowell lab on patterning during embryogenesis
Third year Tissue Repair student Darren Wisniewski studies embryonic stem cell differentiation in the lab of Dr Sally Lowell at the MRC Centre for Regenerative Medicine. Darren is particurlaly interested in developmental patterning. Patterning during embryogenesis is orchestrated by diffusible signals, but diffusion is sensitive to noise. The fact that embryogenesis is remarkably robust suggests that additional layers of regulation reinforce patterning. Darren is co-author on a paper demonstrating that geometrical confinement orchestrates the spatial organisation of initially randomly positioned subpopulations of spontaneously differentiating mouse embryonic stem cells.
The paper can be accessed via the link below: