Tissue Repair student Phoebe Kirkwood co-authors paper on macrophages
The study demonstrates the therapeutic potential of a type of immune cells called macrophages, in a model of liver injury.
The paper describes a protocol whereby pure populations of therapeutic macrophages can be produced in vitro from pluripotent stem cells on a large scale.
Phoebe Kirkwood contributed to the study while carrying out her Tissue Repair rotation in the Forrester lab. The paper was published in npj Regenerative Medicine (Haideri SS, McKinnon AC, A. Taylor H, Kirkwood P, Starkey Lewis PJ, O'Duibhir E, Vernay B, Forbes S, Forrester LM. 2017) and can be accessed below.
Haideri et al: Injection of embryonic stem cell derived macrophages ameliorates fibrosis in a murine model of liver injury.