Dr Mariela Scortti
Principal Investigator
Dr Mariela Scortti
Principal Investigator

- The Chancellor's Building
- 49 Little France Crescent, Edinburgh
- EH16 4SB
Contact details
- Work: +44 131 242 6287
- Email: m.scortti@ed.ac.uk
- Web: Research Explorer publication List
Personal Profile
Mariela has a degree in Veterinary Medicine from the Universidad del Litoral (Argentina, 1990) and a MSc in Veterinary Epidemiology from the Universidad de Chile (Chile, 1996). She later moved to Madrid to investigate animal vaccinology and obtained a PhD from Universidad Complutense de Madrid (Spain, 2000). Mariela joined the group of Prof Vazquez-Boland in 2001, working initially at the University of Leon (Spain) and later at the University of Bristol (2002-2007) and currently at the University of Edinburgh. Her work currently focuses on the molecular determinants of bacterial virulence.
Research Theme
Recent Publications
- Lourenço, A., de Las Heras, A., Scortti, M., Vazquez-Boland, J., Frank, J.F., Brito, L. (2013) Comparison of Listeria monocytogenes Exoproteomes from biofilm and planktonic state: Lmo2504, a protein associated with biofilms. Appl Environ Microbiol. 79:6075-82.
- Salifu SP, Valero-Rello A, Campbell SA, Inglis NF, Scortti M, Foley S, Vázquez-Boland JA. (2013) Genome and proteome analysis of phage E3 infecting the soil-borne actinomycete Rhodococcus equi. Environ Microbiol Rep. 5:170-8.
- Deshayes C., Bielecka M.K., Cain R.J., Scortti M., de Las Heras A., Pietras Z., Luisi B.F., Núñez Miguel R., Vazquez-Boland J.A. (2012) Allosteric mutants show that PrfA activation is dispensable for vacuole escape but required for efficient spread and Listeria survival in vivo. Mol. Microbiol. 85: 461-477.
- Buchrieser, C., Rusniok, C., Garrido, P., Hain, T., Scortti, M., Lampidis, R., Kärst, U., Chakraborty, T.,Cossart, P., Kreft, J., Vazquez-Boland, J.A., Goebel, W., Glaser, P. (2011) Complete genome sequence of the animal pathogen Listeria ivanovii, which provides insights into host specificities and evolution of the genus Listeria. J Bacteriol. 193:6787-8
- Letek, M., Gonzalez, P., MacArthur I., Rodriguez, H., Freeman,T.C, Valero-Rello,A., Blanco, M., Buckley, T., Cheverach, I., Fahey, R., Hapeshi, A., Holdstock, J., Leadon, D., Navas, J., Ocampo, A., Quail, M.A., Sanders, M., Scortti, M., Prescott, J.F., Fogarty, U., Meijer, W.G., Parkhill, J., Bentley, S.D., Vazquez-Boland, J.A. (2010). The genome of a pathogenic Rhodococcus: cooptive virulence underpinned by key gene acquisitions. PLoS Genet. 6:e1001145.
- Ocampo-Sosa, A.A., Lewis, D.A., Navas, J., Quigley, F., Callejo, R., Scortti, M., Fogarty, U., Vazquez-Boland, J.A. (2007) Molecular epidemiology of Rhodococcus equi based on traA, vapA and vapB plasmid markers. J. Infect. Dis. 196: 763-769.
- Scortti, M., Lacharme-Lora, L., Wagner, M., Chico-Calero, I., Losito, P., Vazquez-Boland, J.A. (2006) Coexpression of virulence and fosfomycin susceptibility in Listeria: molecular basis of an antimicrobial in vitro- in vivo paradox. Nat. Med. 12: 515-517.
- Dominguez-Bernal, G. Muller-Altrock, S., Gonzalez-Zorn, B., Scortti, M., Herrmann, P., Monzo, H.J., Lacharme-Lora, L., Kreft , J., Vazquez-Boland, J.A. (2006) A spontaneous genomic deletion in Listeria ivanovii identifies LIPI-2, a species-specific pathogenicity island encoding sphingomyelinase and numerous internalins. Mol. Microbiol. 59: 415-432
- Ermolaeva, E.; Novella, S.; Vega, Y., Ripio, M.T.; Scortti, M.; Vazquez-Boland, J.A. (2004) Negative control of Listeria monocytogenes virulence genes by a diffusible autorepressor. Mol. Microbiol. 52: 601-611.
- Chico-Calero, I., Suarez, M., Gonzalez-Zorn, B., Scortti, M., Slaghuis, J., Vazquez-Boland, J.A. (2002) Hpt, a bacterial homolog of the microsomal glucose-6-phosphate translocase, mediates rapid intracellular proliferation in Listeria. PNAS 99: 431-436.