Infection Medicine

Professor Till Bachmann

My laboratory is interested in diagnostics innovation in the context of targeted and effective antibiotic therapy

Professor Till T. Bachmann

Deputy Head of Infection Medicine & Personal Chair of Molecular Diagnostics and Infection

  • Infection Medicine
  • Deanery of Biomedical Sciences
  • Edinburgh Medical School

Contact details

Address

Street

Chancellor's Building
49 Little France Crescent
Edinburgh BioQaurter

City
Edinburgh
Post Code
EH16 6WA

Personal Profile

Professor Till Bachmann is Deputy Head of the Infection Medicine, Reader in Personalised Medicine in Infectious Diseases, and Programme Director of the Clinical Microbiology & Infectious Diseases MSc at The University of Edinburgh and University of Edinburgh Director of the Zhejiang University -University of Edinburgh Institute Dual PhD programme. Till has a PhD in biosensor research from the University of Stuttgart and The University of Tokyo, as well as a German Habilitation in Analytical Biotechnology. He is an expert in the Point-of-Care detection of infectious diseases and antimicrobial resistance, conducting research at the interface of biomarkers and novel detection modalities. Till gained commercial experience as a founding CEO of Namaxx Genomic GmbH (2001-6) and as Scientific Programme Director for MHC Scotland Ltd (2013-15). He also fulfils a variety of industrial and institutional advisory roles worldwide. For AMR Dx Global he brings in a range of relevant activities and memberships, such as the UK Five Year National AMR Strategy: AMR Diagnostic Collaborative, UK Longitude Prize Panel Scottish Universities Life Science Alliance AMR Steering Group, Edinburgh Infectious Diseases Executive Committee, AMR Theme Leader ‘Rapid diagnostics’ for EID, founder Edinburgh AMR Forum, Edinburgh Global Health Academy and Global Security Steering Groups. Till was also judge for the EU Horizon Prize on Better Use of Antibiotics (2016) and is member of the Devices and Diagnostics Advisory Board for BIRAC/Indian Government, the founder of AMR DxC, the Antimicrobial Resistance Diagnostics Challenge competition as well as the coordinator of the £4m UK-India programme DOSA - ‘Diagnostics for One Health and User Driven Solutions for AMR’ bringing together nine leading academic institutions, five from India and four from the UK.

Teaching

Research

Our research focusses on rapid diagnostics at point of care to enable personalised approaches to medicine. This involves research on novel biosensors, molecular diagnostics, next generation sequencing and biomarkers as well as factors affecting the development and implementation of novel diagnostics. Our main target is the optimisation of antimicrobial therapy to reduce antimicrobial resistance and optimise patient outcome I a wide range of diseases and healthcare settings.

Addional infomation on AMR: AMR Cross-Council Initiative

Research Themes

Current Funding Sources

Lab Members

Collaborations

We collaborate globally with excellent colleagues in academia, healthcare, industry and policy.

Recent Publications

van Belkum A, Bachmann TT, Luedke G, Lisby G, Kahlmeter G, Mohess A, Becker K, Hays JP, Woodford N, Mitsakakis K, Moran-Gilad J, Vila J, Peter H, Rex J, Dunne WM on behalf of the JPIAMR AMR-RDT Working Group, Developmental roadmap for antimicrobial susceptibility testing systems, Nature Reviews Microbiology, accepted

Brennecke J, Kraut S, Zwadlo K, Gandi SK, Pritchard D, Templeton K, Bachmann TT, High yield extraction of E. coli RNA from human whole blood, J Med Microbiol. 2017 66:301-311

Ducrotoy M, Syed S, Bachmann TT, Antimicrobial resistance diagnostics - time to call in the young? Lancet Infect Dis 2016 May 16;5:519-21

Henihan G, Schulze H, Corrigan DK, Giraud G, Terry JG, Hardie A, Campbell CJ, Walton AJ, Crain J, Pethig R, Templeton KE, Mount AR, Bachmann TT, Label- and amplification-free electrochemical detection of bacterial ribosomal RNA, Biosens Bioelectron. 2016 Jul 15;81:487-94.

Huang MY, Henihan G, Macdonald D, Michalowski A, Templeton K, Gibb AP, Schulze H, Bachmann TT, Rapid electrochemical detection of New Delhi metallo-betalactamase genes to enable point of care testing of carbapenem resistant Enterobacteriaceae, Anal Chem. 2015 Aug 4;87(15):7738-45.

Gandi SK, Watson D, Kersaudy-Kerhoas M, Desmulliez MPY, Bachmann TT, Bridle H, Impact of microfluidic processing on bacterial ribonucleic acid expression Biomicrofluidics 2015 May 29;9(3):031102

Corrigan DK, Schulze H, Henihan G, Hardie A, Ciani I, Giraud G, Terry JG, Walton AJ, Pethig R, Ghazal P, Crain J, Campbell CJ, Templeton KE, Mount AR, Bachmann TT. Development of a PCR-free electrochemical point of care test for clinical detection of methicillin resistant Staphylococcus aureus (MRSA). Analyst. 2013 Nov 21;138(22):6997-7005.

Syed SN, Schulze H, Macdonald D, Crain J, Mount AR, Bachmann TT. Cyclic denaturation and renaturation of double-stranded DNA by redox-state switching of DNA intercalators. J Am Chem Soc. 2013 Apr 10;135(14):5399-407.

Peter H, Berggrav K, Thomas P, Pfeifer Y, Witte W, Templeton K, Bachmann TT. Direct detection and genotyping of Klebsiella pneumoniae carbapenemases from urine by use of a new DNA microarray test. J Clin Microbiol. 2012 Dec;50(12):3990-8.

Schulze H, Barl T, Vase H, Baier S, Thomas P, Giraud G, Crain J, Bachmann TT. Enzymatic on-chip enhancement for high resolution genotyping DNA microarrays. Anal Chem. 2012 Jun 5;84(11):5080-4

University of Edinburgh Roles

External Roles