MRC Institute of Genetics & Molecular Medicine
MRC Institute of Genetics & Molecular Medicine

Vacancies

Current vacancies within the IGMM.

A summary of current IGMM vacancies is provided below. Queries can be directed to the contact provided within the job vacancy or email IGMM Human Resources: IGMMHR@igmm.ed.ac.uk

Please note that all IGMM vacancies are advertised on the University of Edinburgh eRecruitment website, where you can also set up personalised email notifications for future vacancies of interest.

 Research Fellow (Vacancy Ref: 049059  )

Centre Name: MRC Human Genetics Unit at the University of Edinburgh

Closing date:  18 September 2019

Overview:

A 1 year position is available in the laboratory of Professor Nick Gilbert (MRC Human Genetics Unit) and Professor Davide Marenduzzo (School of Physics), at the University of Edinburgh. The project will utilize cutting edge bioinformatics and computational biology approaches to investigate DNA, RNA and chromatin organisation in mammalian cells.

You will be part of a collaborative and vibrant research team developing new experimental approaches and computational techniques to investigate DNA, RNA and chromatin structure. http://www.hgu.mrc.ac.uk/people/n.gilbert.html https://www.ph.ed.ac.uk/people/davide-marenduzzo http://www.nutshell-videos.ed.ac.uk/nick-gilbert-packaging-the-genome/

Prospective candidates will have a PhD and experience in the areas of bioinformatics / molecular biology, and will also have proven expertise in conducting computational analyses to investigate chromatin structure and mechanisms of gene regulation. Applicants must be innovative, have experience in developing new analysis techniques and be competent at investigating next generation sequencing data. Candidates should have a good understanding of mathematical and computational analysis techniques and have an appreciation of higher-order chromatin structure, histone modifications and gene regulation.

Although the position is currently for 1-year we hope it will be extended. For informal enquiries please contact Nick Gilbert (nick.gilbert@ed.ac.uk) or Davide Marenduzzo (davide.marenduzzo@ed.ac.uk).

Salary: £33,199 - £39,609

Further information

  Research Fellow in Genome Informatics (Vacancy Ref: 049077)

Centre Name: Centre for Genomic & Experimental Medicine at the University of Edinburgh

Closing date: 19 September 2019

Overview:

An exciting opportunity is open for a Research Fellow in Genome Informatics to work in a Chief Scientist Office (CSO)-funded post as part of the Scottish Genomes Partnership (SGP). The post holder will work alongside bioinformaticians in the research group of Professor Tim Aitman in the Centre for Genomic and Experimental Medicine, the Bioinformatics Core in the MRC Institute for Genetics and Molecular Medicine, and clinicians and scientists in the Scottish NHS, to analyse whole genome sequences and to develop pipelines for clinical interpretation. The successful applicant will be a highly motivated individual, holding a PhD in Bioinformatics or related field (or equivalent practical experience), with proven experience in mining of genome data repositories and statistical methodologies to support experimental design and data interpretation. The ideal candidate will have excellent communication skills with a strong publication track record in bioinformatics/molecular genetics/molecular biology research.

Salary: £33,199 - £39,609

Further information

  Cross-Disciplinary Post-Doctoral Fellowship (XDF) (Vacancy Ref: 049043)

Centre Name: The MRC Institute of Genetics & Molecular Medicine at the University of Edinburgh

Closing date: 20 September 2019

Overview:

Do you wish to grow your analytical skills to make the next breakthrough in biomedical research?

We are seeking up to 3 Fellows who have acquired strong data analytical and/or computational skills from their doctoral studies in physics, mathematics, informatics, computer science, engineering, or similar.

Our pledge: We will train you to become a leader in Complex Data Quantitative Biomedicine.

Our request: You will wish to solve the most pressing questions in biomedicine.

If you have these analytical skills, and seek to broaden your scientific horizons and make a real impact on people’s health, then please do apply.

Background

The beginning of the 21st century has seen enormous advances in science and technology. With the completion of the Human Genome Project and implementation of multiple “Big Data” approaches in biomedical sciences, there is now a pressing need to train a new generation of mathematically-minded biomedical scientists who will be able to bridge the gap between life sciences and mathematics/physics/informatics, and efficiently link modern biomedical research with complex data research technologies. To address this need a pioneering Cross-Disciplinary Post-Doctoral Fellowships programme (XDF, http://www.xdf.training) has been initiated in 2018 at the University of Edinburgh with matching financial support from the Medical Research Council (with subsequent incorporation of other funds). This is the third recruitment phase, with 4 XDFs and 3 XDFs already in post from recruitment in 2018 and early 2019, respectively.

The University of Edinburgh is one of the world leading research universities (ranked 4th in UK for its research power) and is at the forefront of both computational sciences and health sciences. Informatics is the largest and strongest computer science department in the UK (1st for research power according to REF2014), with particular strengths in data science and computational biology. Clinical medicine has been ranked 4th in the UK (research power) with Institute of Genetics and Molecular Medicine (IGMM) being one of the biggest biomedical research establishments in the country. The XDF Programme lead, Prof. Ponting, was trained first in particle physics before pursuing a successful career in biomedicine, so knows first-hand the skills necessary for Fellows to transition into “Complex Data Biomedicine”. The programme is led by a board of Directors, including Profs Jane Hillston and Guido Sanguinetti (School of Informatics) and Profs Margaret Frame and Tim Aitman (School of Molecular, Genetic and Population Health Sciences/IGMM), who will provide Fellows with diverse perspectives.   

Salary: £33,199 - £39,609

Further information

Biostatistician / Epidemiologist (Vacancy Ref: 049304)

Centre Name: MRC Human Genetics Unit at the University of Edinburgh

Closing date:  26 September 2019

Overview:

We are seeking a high calibre statistician or epidemiologist to join the Diabetes Medical Informatics and Epidemiology team within the Institute of Genetics and Molecular Medicine at University of Edinburgh. The Unit is an internationally recognised leader in research in diabetes using large biorepositories linked to electronic health care record data. The post would suit a post-doctoral biostatistician or epidemiologist with good skills in analysis of large and complex datasets. The post provides a great opportunity for an enthusiastic researcher to develop core expertise in the rapidly expanding field of large scale usage of electronic health records for research linked to high dimensional datasets including genetic and metabolomics data. Key elements of the job are to design and conduct data analyses and to write papers either as lead author or co-author. The successful applicant will have a PhD (or near completion) in a numerate discipline, i.e. statistics, mathematics, computer science, bioinformatics, epidemiology or equivalent and will have experience in analysing large datasets and preparing data output for publications.

This is a fixed-term post for 2 years.

Informal enquiries can be made to helen.colhoun@igmm.ed.ac.uk

Salary: £33,199 - £39,609

Further information

Clinical Research Fellow (Vacancy Ref: 049396)

Centre Name: Cancer Research UK Edinburgh Centre at the University of Edinburgh

Closing date: 03 October 2019

Overview:

A clinical research fellow post is available to join the Colorectal Cancer research groups at the Edinburgh Cancer Research Centre (ECRC) within the Institute of Genetics and Molecular Medicine, Western General Hospital campus. This post is a fixed-term appointment for 3 years and is funded by the Scottish Government as a key component of the implementation of quantitative faecal immunochemical testing (qFIT) into the symptomatic population. This is an exciting opportunity for a surgical or gastroenterology trainee to undertake a period of focussed clinical research with the added value of translational research oppotunities. The successful applicant will undertake high quality original research, investigating specific objectives and produce material for publication. The post-holder will be working closely with Miss Farhat Din and Professor Malcolm Dunlop at the Colorectal Surgery Unit at the Western General Hospital and the Edinburgh CRUK Centre within the IGMM.

This post is available on a fixed term basis for 3 years and it is expected the applicant will enrol for a higher degree.

Informal queries to Farhat.Din@igmm.ed.ac.uk

Salary: AMN2 £34,125 to £50,563

Further information

Research Assistant (Vacancy Ref: 049557)

Centre Name: MRC Human Genetics Unit at the University of Edinburgh

Closing date:  11 October 2019

Overview:

An exciting opportunity is open for a Research Assistant to join an interdisciplinary team of researchers in the MRC Human Genetics Unit. The initial purpose of this role is assist in revealing the earliest molecular changes that eventually lead to cancer. The successful applicant will help to model the initiation of liver cancer in mice by following their effects on DNA and RNA in bulk and/or single cell samples. The team hopes to shed light on whether pre-neoplastic sub-clones cooperate or compete over their evolution. The successful applicant will be a highly motivated individual, with good wet lab experience in molecular and/or cell biology. Expertise in next generation sequencing experiments and interest in genome-scale data will be an advantage. The ideal candidate will have excellent communication skills with experience of oral presentations and writing scientific documents and will have a good BSc in Molecular Genetics, Molecular Biology, or a closely related field.

The post is initially for 3 years and the role will evolve into assisting with other interdisciplinary projects spanning across HGU research groups. For informal enquiries please contact:

Prof Chris Ponting (chris.ponting@igmm.ed.ac.uk) or Ava Khamseh (ava.khamseh@igmm.ed.ac.uk) or Luke Boulter (luke.boulter@igmm.ed.ac.uk) or Martin Taylor (martin.taylor@igmm.ed.ac.uk).

Further information on the MRC HGU’s work and research in these groups is available at: https://www.ed.ac.uk/mrc-human-genetics-unit

Salary: £28,331 - £32,816

Further information

Genomic Data and Application Architect (Vacancy: 049589)

Centre Name: MRC Human Genetics Unit at the University of Edinburgh

Closing date:  14 October 2019

Overview:

The Institute of Genetics and Molecular Medicine (IGMM; http://www.igmm.ac.uk/) at the University of Edinburgh has an exciting opportunity for an experienced, highly motivated Genomic Data and Application Architect to develop a genomic data analysis and repository services. The scale of biomedical genomic data production is accelerating as it moves into mainstream clinical usage; the data is sensitive and must be handled securely under regulatory guidance with strict governance. The post holder will have a critical role in our evolving translational genomics team: establishing pipelines and databases for genomic sequence analysis at IGMM, and enabling the future of genetic diagnostic services in NHS Scotland. They will work to establish best practice analysis protocols, databases and interfaces for IGMM projects on a range of human diseases; in parallel with NHS staff establishing a genomic data repository in the NHS Education Scotland Digital Service (NDS) National Digital Platform cloud service. The post holder will work closely with bioinformatics, IT, and clinical research staff at IGMM, while interfacing with repository developers at the University of Cambridge, and the cloud development team at NDS.

The IGMM constitutes one of the largest aggregates of human molecular genetics and biomedical research capacity in the UK with over 70 Principal Investigators and 500 staff and PhD students. The successful applicant will join the IGMM Bioinformatics Analysis Core, which contributes computational expertise to collaborative projects with IGMM scientists, and also forms an important link between academic and NHS colleagues, as well as the Edinburgh Genomics (http://genomics.ed.ac.uk/) high throughput sequencing facility and the Edinburgh Clinical Research Facility (https://www.wtcrf.ed.ac.uk/). They will work from the state of the art Systems Medicine building at IGMM, designed around our thriving community of computational biologists.

The post offers an excellent opportunity to work at the intersection of academic genomics research and health care information systems. It would suit an experienced bioinformatician with interests in such systems, or a data and applications architect with strong interests in medical genomics. Good project management, organizational, and interpersonal skills are essential.

Informal enquiries to: Alison.Meynert@igmm.ed.ac.uk or igmmhr@igmm.ed.ac.uk

Salary: £33,797 - £40,332

Further information