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Semester 1

Molecular Genetics 3 (BILG09002)

Subject

Biology

College

SCE

Credits

20

Normal Year Taken

3

Delivery Session Year

2022/2023

Pre-requisites

Equivalent of the courses listed above

Course Summary

A core course in molecular genetics. The course covers chromosome structure and organisation; gene expression and RNA processing in prokaryotes and eukaryotes; genetic engineering; genetic stability and instability; transposable elements and DNA rearrangements; genetic analysis; mouse genetics and transgenesis. The lectures are complemented by tutorials and by practical sessions that provide hands-on experience of genetical and molecular genetical manipulations.

Course Description

A basic understanding of Molecular Genetics is essential to many areas of scientific study. This junior honours course aims to extend the knowledge gained in previous courses, particularly Genes and Gene Action 2, and to promote a more detailed understanding of this field of Biology. Molecular Genetics 3 is a requirement for Genetics, Molecular Genetics, Cell Biology, Molecular Biology, Development, Regeneration and Stem Cells and Biotechnology senior honours programmes and also provides an advanced background to several other courses.The major topics covered by the course are:- regulation of gene expression and RNA processing- chromosome structure, organisation and segregation- genetic stability and instability- genetic engineering- mouse genetics and transgenesisThe course will run based on an hybrid model, comprising a series of lectures and tutorials online, as well as in-person practical sessions that provide hands-on experience of many of the molecular manipulations used in modern genetics and molecular biology. All students, irrespective of whether attending in-person or not, will interact fully with the practicals using the videos, resources, discussion, activities and live-streamed or recorded material available. The tutorial sessions are important towards developing the skills required for data interpretation, problem solving and group working, while the assessed essay will develop your scientific critique and writing skills. The course will be assessed by continuous assessment.

Assessment Information

Written Exam 40%, Coursework 60%, Practical Exam 0%

Additional Assessment Information

The course is fully assessed by weekly in-course work. In-course components of assessment:- 1000 word essay (25%)- Lecture quizzes (5%)- Practicals quizzes (10% total: 7% Block 1 Lab and 3% Block 2 lab)- Data Handling Test (15%)- Tutorials (5%)- Final Exam (40%)

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