Genetic Health in the 21st Century
Genetic Health in the 21st Century (GS:21CGH) gathered genetic information about the people of different areas of Scotland, to give researchers a clearer picture of the genetic make-up of the Scottish population.
Genetic Health in the 21st Century (GS:21CGH) is a resource of control DNA and genetic and phenotypic information, from nearly 2,000 consenting individuals from 6 different places in Scotland. It is designed to help establish the genetic profile of a control population living in Scotland in relation to health and disease. Recruitment took place in Aberdeen, Banff, Dundee, Edinburgh, Glasgow and Peterhead.
Two blood samples (for DNA, PBLs and plasma) were collected from each participant as well as a urine sample (Aberdeen only). Phenotype information was also collected, including basic physical observations, cognitive function measurements and answers to a clinical/lifestyle questionnaire. Data obtained from participants in the clinics was entered into the 21CGH database using electronic collection methods. Consent was also obtained for access and extraction of de-identified information from patient medical records.
DNA was extracted from all blood samples and archive and working stocks prepared. Purified blood cells were stored and can be used to make lymphoblastoid cell lines (LCL). These will primarily be a resource for proteomics work but they may also be used for DNA extraction for future research.
The 21CGH LCL resource should limit the need to obtain further fresh control blood/DNA samples and will provide a knowledge base to aid in the design of future genetic studies.
Geographical Profile of Cohort
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