Generation Scotland

2013 Symposium Highlights Value of GS Resources

The Generation Scotland Symposium 2013 highlighted some of the best research using GS resources to date and the great potential of recent genotyping of 10,000 GS participants.

1 October 2013

 

The GS Symposium 2013 highlighted some of the best research using GS resources to date and the great potential of recent genotyping of 10,000 GS participants. The symposium, which was held on 30 September at the Royal College of Surgeons in Edinburgh, attracted 150 academic and commercial researchers.

 

The symposium marks the recent completion of genome wide association data on 10,000 Scottish Family Health Study participants, funded by the Medical Research Council Human Genetics Unit in Edinburgh and conducted by their Quantitative Trait Loci group and presented at the meeting by principal investigator Dr Caroline Hayward.

 

Delegates were treated to several high profile examples of how GS resources have been used. Professor Tim Aitman described how he used GS samples and data to investigate familial hypercholesterolaemia showing targeted sequencing is feasible.

 

Others showed the contribution GS has made to research in developmental disorders, lung disease and the effects of maternal diabetes on resulting offspring. Professor Jane Norman of Tommy's Centre in Edinburgh talked about how good it is to have a local (Scottish) resource of samples and data which can be linked to NHS data.

 

GS collaborators introduced the newly formed Expert Working Groups in Cognition, Pain and Mental Health. Expert Working Groups are investing expertise and research resource in quality control, validation and first class research in their area of expertise, greatly increasing the value of the resource for future research.

 

Keynote speaker Professor Nick Hastie, Director of the Institute of Genetics and Molecular Medicine in Edinburgh, explored the potential of human genetics to help combat disease, answering the question "What can GS do for human genetics research?" with "Families, technology, NHS record linkage and re-contact - GS resources are important".