Generation Scotland


Generation Scotland incorporates three Research Tissue Banks: the Scottish Family Health Study; Genetic Health in the 21st Century; and the Donor DNA Databank.

Scottish Family Health Study

The Scottish Family Health Study (GS:SFHS) is a collection of genetic, medical, family history and lifestyle information which is allowing scientists to study how our genes and the environment combine to affect our chance of getting common diseases. Over 24,000 volunteers participated in GS:SFHS.

Genetic Health in the 21st Century

The aim of Genetic Health in the 21st Century (GS:21CGH) is to gather genetic information about the inhabitants of different areas of Scotland, giving researchers a clearer picture of the genetic make-up of the Scottish population. GS:21CGH has recruited nearly 2,000 individuals from 6 different regions of Scotland.

Donor DNA Databank

The Donor DNA Databank (GS:3D) is a collection of thousands of DNA samples from the general population which is available to researchers who are investigating human diseases with a genetic component. GS:3D holds samples of around 5000 volunteers.


The table below gives information on the number of participants, the type of samples and data collected, and the type of research these data are used for.



Scottish Family Health Study


Genetic Health in the 21st Century


Donor DNA Databank


Number of participants ~24,000 ~2,000 ~5,000
Samples Blood; serum; DNA; urine; cryo-preserved blood; biochemical data Blood; plasma; DNA; cells DNA; plasma
Data Intensive phenotype; clinical measures; mental health; cognition Moderate phenotype; clinical measures; personality; cognition Minimal phenotype
Types of research Identify genetic variants; enhanced power for linkage & association studies; CNV inheritance testing Control dataset Control samples for replication



You might also be interested in:

Detailed information about GS:SFHS

Detailed information about GS:21CGH

Detailed information about GS:3D

The Access Process