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2014 publication highlights

Selected publications for 2014, alphabetically by first author.

Please note that not all journals provide open access.

Caballero IM, Manuel MN, Molinek M, Quintana-Urzainqui I, Mi D, Shimogori T, Price DJ. (2014). Cell-Autonomous Repression of Shh by Transcription Factor Pax6 Regulates Diencephalic Patterning by Controlling the Central Diencephalic Organizer. Cell Rep. 8(5):1405-18.

Caballero et al.

Cachat E, Liu W, Hohenstein P, Davies JA. (2014). A library of mammalian effector modules for synthetic morphology. J Biol Eng.; 8(1):26

Cachat et al.

Chen SJ, Yang JF, Kong FP, Ren JL, Hao K, Li M, Yuan Y, Chen XC, Yu RS, Li JF, Leng G, Chen XQ, Du JZ. (2014). Overactivation of corticotropin-releasing factor receptor type 1 and aquaporin-4 by hypoxia induces cerebral edema.Proc Natl Acad Sci U S A. 111(36):13199-204.

Cheng et al.

Clarkson YL, Perkins EM, Cairncross CJ, Lyndon AR, Skehel PA, Jackson M. (2014) β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations. Hum Mol Genet. 23(14):3875-82.

Clarkson et al.

Clegg JM, Conway CD, Howe KM, Price DJ, Mason JO, Turnbull JE, Basson MA, Pratt T. (2014). Heparan Sulfotransferases Hs6st1 and Hs2st Keep Erk in Check for Mouse Corpus Callosum Development. Jneurosci, 34(6): 2389-2401.

Clegg et al.

Crocker-Buque A, Brown SM, Kind PC, Isaac JT, Daw MI. (2014). Experience-Dependent, Layer-Specific Development of Divergent Thalamocortical Connectivity. Cereb Cortex. 2014 Mar 7 [Epub ahead of print]

Crocker-Buque et al.

Deighton RF, Márkus NM, Al-Mubarak B, Bell KF, Papadia S, Meakin PJ, Chowdhry S, Hayes JD, Hardingham GE. (2014). Nrf2 target genes can be controlled by neuronal activity in the absence of Nrf2 and astrocytes. Proc Natl Acad Sci U S A. 111(18):E1818-20

Deighton et al.

Diggle CP, Moore DJ, Mali G, Zur Lage P, Ait-Lounis A, Schmidts M, Shoemark A, Garcia Munoz A, Halachev MR, Gautier P, Yeyati PL, Bonthron DT, Carr IM, Hayward B, Markham AF, Hope JE, von Kriegsheim A, Mitchison HM, Jackson IJ, Durand B, Reith W, Sheridan E, Jarman AP, Mill P. (2014). HEATR2 Plays a Conserved Role in Assembly of the Ciliary Motile Apparatus.PLoS Genet. 10(9):e1004577.

Diggle et al.

Duncan PJ, Sengul S, Tabak J, Ruth P, Bertram R, Shipston MJ. (2014) Large conductance Ca2+ -activated K+ channels (BK) promote secretagogue-induced transition from spiking to bursting in murine anterior pituitary corticotrophs. J Physiol. 2014 Dec 24 [Epub ahead of print]

Duncan et al.

Flak JN, Patterson CM, Garfield AS, D'Agostino G, Goforth PB, Sutton AK, Malec PA, Wong JM, Germani M, Jones JC, Rajala M, Satin L, Rhodes CJ, Olson DP, Kennedy RT, Heisler LK, Myers MG Jr. (2014). Leptin-inhibited PBN neurons enhance responses to hypoglycemia in negative energy balance. Nat Neurosci. 17(12):1744-50.

Flak et al.

Garfield AS, Shah BP, Madara JC, Burke LK, Patterson CM, Flak J, Neve RL, Evans ML, Lowell BB, Myers MG Jr, Heisler LK. (2014). A Parabrachial-Hypothalamic Cholecystokinin Neurocircuit Controls Counterregulatory Responses to Hypoglycemia. Cell Metab; 20(6):1030-1037.

Garfield et al.

Gonzalez-Sulser A, Parthier D, Candela A, McClure C, Pastoll H, Garden D, Sürmeli G, Nolan MF. (2014) GABAergic projections from the medial septum selectively inhibit interneurons in the medial entorhinal cortex. J Neurosci. 34(50):16739-43

Gonzalez-Sulser et al.

Howie J, Reilly L, Fraser NJ, Vlachaki Walker JM, Wypijewski KJ, Ashford ML, Calaghan SC, McClafferty H, Tian L, Shipston MJ, Boguslavskyi A, Shattock MJ, Fuller W. (2014). Substrate recognition by the cell surface palmitoyl transferase DHHC5. Proc Natl Acad Sci U S A. 2014 Nov 24. [Epub ahead of print]

Howie et al.

Hunter, G., Aghamaleky Sarvestany, A., Roche, S.L., Symes, R.C. & Gillingwater, T.H. (2014) SMN-dependent intrinsic defects in Schwann cells in mouse models of spinal muscular atrophy. Human Molecular Genetics 23:2235-2250.

Hunter et al.

James OT, Livesey MR, Qiu J, Dando O, Bilican B, Haghi G, Rajan R, Burr K, Hardingham GE, Chandran S, Kind PC, Wyllie DJ. (2014). Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell-derived excitatory cortical neurones. J Physiol. 592(Pt 19):4353-63.

James et al.

Kokotos AC, Cousin MA. (2014). Synaptic vesicle generation from central nerve terminal endosomes. Traffic. 2014 Oct 24. [Epub ahead of print]

Kokotos et al.

Krashes, M. J., B. P. Shah, J. C. Madara, D. P. Olson, D. E. Strochlic, A. S. Garfield, L. Vong, H. Pei, M. Watabe-Uchida, N. Uchida, S. D. Liberles, B. B. Lowell (2014). An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger. Nature 507(7491):238-42.

Krashes et al.

Lin PH, Duann P, Komazaki S, Park KH, Li H, Sun M, Sermersheim M, Gumpper K, Parrington J, Galione A, Evans AM, Zhu MX, Ma J. (2014). Lysosomal two-pore channel subtype 2 (TPC2) regulates skeletal muscle autophagic signaling. J Biol Chem. 2014 Dec 5. [Epub ahead of print]

Lin et al.

Lindström NO, Chang CH, Valerius MT, Hohenstein P, Davies JA. (2014). Node retraction during patterning of the urinary collecting duct system. J Anat. 2015 Jan;226(1):13-21

Lindström et al.

Livesey MR, Bilican B, Qiu J, Rzechorzek NM, Haghi G, Burr K, Hardingham GE, Chandran S, Wyllie DJ. (2014). Maturation of AMPAR Composition and the GABAAR Reversal Potential in hPSC-Derived Cortical Neurons. J Neurosci. 34(11).

Livesey et al.

Livingstone DE, Barat P, Di Rollo EM, Rees GA, Weldin BA, Rog-Zielinska EA, MacFarlane DP, Walker BR, Andrew R. (2014). 5α-Reductase type 1 deficiency or inhibition predisposes to insulin resistance, hepatic steatosis and liver fibrosis in rodents.Diabetes. 2014 Sep 19 [Epub ahead of print]

Livingstone et al.

Nicholson-Fish JC, Cousin MA, Smillie KJ. (2015) Phosphatidylinositol 3-Kinase Couples Localised Calcium Influx to Activation of Akt in Central Nerve Terminals. Neurochem Res. 2015 Jul 22. [Epub ahead of print]

Nicholson-Fish et al.

Ogunbayo OA, Zhu Y, Shen B, Agbani E, Li J, Ma J, Zhu MX, Evans AM. (2014). Organelle-specific subunit interactions of the vertebrate Two Pore Channel family. J Biol Chem. 2014 Dec 1 [Epub ahead of print]

Ogunbayo et al.

Roche, S.L., Sherman, D.L., Dissanayake, K., Soucy, G., Desmazieres, A., Lamont, D.J., Peles, E., Julien, J-P., Wishart, T.M., Ribchester, R.R., Brophy, P.J. & Gillingwater, T.H. (2014). Loss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junction. J Neurosci. 34(38):12904-18.

Roche et al.

Sande TA, Scott AC, Laird BJ, Wan HI, Fleetwood-Walker SM, Kaasa S, Klepstad P, Mitchell R, Murray GD, Colvin LA, Fallon MT. (2015) The characteristics of physical activity and gait in patients receiving radiotherapy in cancer induced bone pain. Radiother Oncol. 2014 111(1):18-24.

Sande et al.

Sanhueza, M., L. Zechini, T. Gillespie, G. Pennetta (2014). Gain-of-function mutations in the ALS8 causative gene VAPB have detrimental effects on neurons and muscles. Biol Open. 3(1):59-71

Sanhueza et al.

Saxena A, Denholm B, Bunt S, Bischoff M, VijayRaghavan K, Skaer H. (2014). Epidermal Growth Factor Signalling Controls Myosin II Planar Polarity to Orchestrate Convergent Extension Movements during Drosophila Tubulogenesis. PLoS Biol.;12(12):e1002013

Saxena et al.

Tahmasebi S, Alain T, Rajasekhar VK, Zhang JP, Prager-Khoutorsky M, Khoutorsky A, Dogan Y, Gkogkas CG, Petroulakis E, Sylvestre A, Ghorbani M, Assadian S, Yamanaka Y, Vinagolu-Baur JR, Teodoro JG, Kim K, Yang XJ, Sonenberg N. (2014). Multifaceted Regulation of Somatic Cell Reprogramming by mRNA Translational Control. Cell Stem Cell. 14(5):606-16

Tahmasebi et al.

Upreti R, Hughes KA, Livingstone DE, Gray CD, Minns FC, Macfarlane DP, Marshall I, Stewart LH, Walker BR, Andrew R. (2014). 5α-reductase type 1 modulates insulin sensitivity in men. J Clin Endocrinol Metab. 99(8):E1397-406.

Upreti et al.

Wishart, T.M., Mutsaers, C.A., Riessland, M., Reimer, M.R., Hunter, G., Hannam, M.L., Eaton, S., Fuller, H.R., Roche, S.L., Somers, E., Morse, R., Young, P.J., Lamont, D.J., Hammerschmidt, M., Joshi, A., Hohenstein, P., Morris, G.E., Parson, S.H., Skehel, P.A., Becker, T., Robinson, I.M., Becker, C.G., Wirth, B. & Gillingwater, T.H. (2014) Dysregulation of ubiquitin homeostasis and β-catenin signalling promote spinal muscular atrophy. Journal of Clinical Investigation 124: 1821-1834.

Wishart et al.