My current research focuses on the understanding of neuronal network function in neurodevelopmental disorders.
- 2018 - Present: Postdoctoral fellow with Peter Kind, CDBS, University of Edinburgh
- Postdoctoral fellow with Dr Laure Rondi-Reig. Paris Sorbonne University, France.
- Postdoctoral fellow with Prof Richard Apps and Prof Bridget Lumb. University of Bristol, UK.
- PhD, University of Bristol. Supervisors: Prof Richard Apps and Prof Matt Jones.
- BSc in Biological Sciences with Hons in Neuroscience (1st), University of Edinburgh.
The overall aim of my research is to understand how groups of neurones in disparate brain regions co-ordinate their activity to form distributed, functionally relevant neuronal networks. In particular, I am interested in cerebro-cerebellar and fear-related brain circuits. My current research aim is try to explore neural dynamics within such networks in models of autism spectrum disorder and intellectual disability. To do so, I am using a variety of multi-site, in vivo electrophysiology, viral and optogenetic techniques in awake, behaving rodents.
Torres AT, Watson TC*, Rondi-Reig L*. (2021) Delta oscillations coordinate intra-cerebellar and cerebello - hippocampal network dynamics during sleep. bioRxiv 2021.05.04.442571.* Equal contribution.
Hristova K*, Martinez-Gonzalez C*, Watson TC* et al. (2021). Medial Septal GABAergic Neurons Reduce Seizure Durations Upon Wireless Optogenetic Closed-Loop Stimulation in Epilepsy. Brain 144:1576-1589. * Equal contribution.
Till S*, Katsanevaki D*, Buller-Peralta, I, Watson, TC et al. Heterozygous deletion of SYNGAP enzymatic domains in rats causes selective learning, social and seizure phenotypes. bioRxiv 2020.10.14.339192. * Equal contribution.
Anstey NJ, Kapgal V, Tiwari S, Watson TC et al. (2020). Imbalance of flight-freeze responses and their cellular correlates in the Nlgn3-/y rat model of autism. bioRxiv 2020.08.27.267880.
Watson TC, Obiang P, Torres AT, Watilliaux A, Coulon P, Rochefort C, Rondi-Reig L. (2019). Anatomical and physiological foundations of cerebello-hippocampal interaction. eLife 8:e41896.
- Watson TC• and Apps R. (2019). Cerebro-cerebellar connections. In: Handbook of Cerebellar Disorders (Manto M, Ed). *Co-Corresponding author.
- Watson TC•, Cerminara NL, Lumb BM, Apps R. (2016). Neural correlates of fear in the periaqueductal grey. J. Neuroscience. Dec 14; 36. *Corresponding author.
- Lawrenson CL, Watson TC, Apps R. (2016). Transmission of Predictable Sensory Signals to the Cerebellum via Climbing Fiber Pathways Is Gated during Exploratory Behavior. J. Neuroscience. Jul 27; 36.
- Koutsikou S*, Watson TC*, Crook JJ, Leith JL, Lawrenson CL, Apps R, Lumb BM. (2015). The Periaqueductal Gray Orchestrates Sensory and Motor Circuits at Multiple Levels of the Neuraxis. J. Neuroscience. Oct 21; 35 * Co-first authors.
- Watson TC, Koutsikou S, Apps, R, Jones MW. Eds. (2015). Distributed Networks: New Outlooks on Cerebellar Function. E-Book. Lausanne: Frontiers Media.
- Watson TC. (2015). “And the little brain said to the big brain...” Frontiers in systems Neuroscience. 9:78.
- Watson TC, Apps, R, Jones MW. (2014). Back to front: cerebellar connections and interactions with the prefrontal cortex. Frontiers in Systems Neuroscience. 8:4.
- Watson TC, Koutsikou S, Cerminara NL, Flavell CR, Crook JJ, Lumb BM, Apps R. (2013). The olivo-cerebellar system and its relationship to survival circuits. Frontiers in Neural Circuits.7:72.
- Watson TC, Jones MW, Apps R. (2009). Electrophysiological mapping of novel prefrontal -cerebellar pathways. Frontiers in Integrative Neuroscience. 3:18.