Investigating the neuroendocrine control of feeding behaviour
- 2020-Current: Postdoctoral Research Fellow (Centre for Discovery Brain Sciences, Ludwig Lab)
- 2015-2020: PhD Student (Roslin Institute/ Centre for Discovery Brain Sciences, Brunton Lab)
- 2012- 2015: Research Assistant, Duke-NUS Graduate Medical School, Singapore
- 2009-2012: BSc (Hons) Biomedical Sciences, National University of Singapore
I am interested in how hormones affect diverse physiological processes and behavioural outcomes throughout the life course.
I am currently investigating the role of oxytocin in regulating appetite and obesity, working within a multidisciplinary team as part of the Leng and Ludwig research groups. I focus on the in vivo aspects of the project, employing chemogenetic techniques coupled with behavioural and biochemical assays in the rat model.
I completed my PhD training with Dr Paula Brunton, where I investigated the role of steroids in mediating the outcomes of stress during pregnancy. I also developed and validated a liquid chromatography-mass spectrometry method to measure neurosteroids, shedding light on the complex interaction between steroids, stress, and biological sex.
- Sze Y, Brunton PJ. Effects of prenatal stress on neuroactive steroid responses to acute stress in adult male and female rats (2021) J Neuroendocrinol.
- Scott H, Phillips TJ, Sze Y, Alfieri A, Rogers MF, Volpato V, Case CP, Brunton PJ (2020) Maternal antioxidant treatment prevents the adverse effects of prenatal stress on the offspring’s brain and behavior. Neurobiol Stress
- Sze Y, Brunton PJ (2019) Sex, Stress and Steroids. Eur J Neurosci.
- Sze Y, Gill AC, Brunton PJ (2018) Sex-dependent changes in neuroactive steroid concentrations in the rat brain following acute swim stress. J Neuroendocrinol.