Centre for Discovery Brain Sciences
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Katherine Bonnycastle

Elucidating presynaptic dysfunction in various genetic preclinical models of intellectual disability.

 

Dr Katherine Bonnycastle

Postdoctoral Researcher - Cousin lab

  • Hugh Robson Building
  • 15 George Square
  • Edinburgh, EH8 9XD

Contact details

Personal profile

  • 2018-present: Postdoctoral Research, Centre for Discovery Brain Sciences, University of Edinburgh
  • 2014-2018: PhD Biomedical Sciences (Integrative Physiology), University of Edinburgh, Edinburgh
  • 2013-2014: MScR Biomedical Sciences (Integrative Physiology) University of Edinburgh, Edinburgh
  • 2010-2013: BA & BSc (Hons) Cognitive Science, McGill University, Montreal, Canada

Research

My research focusses on elucidating presynaptic dysfunction in various genetic preclinical models of intellectual disability, autism spectrum disorder and epilepsy. Using live-cell imaging techniques, I am studying whether synaptic vesicle recycling is altered in any of these models.

Publications

Bonnycastle K, Davenport EC, Cousin MA. Presynaptic dysfunction in neurodevelopmental disorders: Insights from the synaptic vesicle life cycle. J Neurochem. 2020. doi: 10.1111/jnc.15035 [doi].