I am investigating whether normal astrocytic functions are altered in Alzheimer’s Disease (AD). Contact type Person First name Monique Surname Hooley Role PhD Student - Hardingham & Spires-Jones Labs Organisation 1 1 George Square Organisation 2 Edinburgh Organisation 3 EH8 9XD Email Monique.hooley@ed.ac.uk Personal profile Wellcome Trust 4 Year Translational Neuroscience PhD student (2016-present) Pharmacology Msci, University of Bristol (2012-2016) Industrial placement at Pfizer (2014-2015) Research Astrocytes are the most abundant cell type in the brain. They are involved in a number of functions, including providing nutrients to nervous tissue and regulating extracellular ion balance. I am investigating whether normal astrocytic functions are altered in Alzheimer’s Disease (AD). I am utilising in vitro and in vivo models of AD to conduct unbiased searches for alterations in astrocytic gene expression in the context of synapse loss. I will compare these results to those found in human AD cases to assess the suitability of these models. Image Image
Contact type Person First name Monique Surname Hooley Role PhD Student - Hardingham & Spires-Jones Labs Organisation 1 1 George Square Organisation 2 Edinburgh Organisation 3 EH8 9XD Email Monique.hooley@ed.ac.uk