Kai Boon Tan
Kai Boon Tan's biography and research focus.
- 2017 – Present University of Edinburgh PhD in Developmental Neurobiology
- 2015 – 2016 Imperial College London Master in Biomedical Research (Immunotoxicology and Neuroscience)
- 2014 – 2015 Monash University Research and Teaching Assistant in Immunology
- 2011 – 2014 Monash University BSc (1st Class Honors) Biomedical Sciences
I study the molecular mechanisms underlying the mammalian neocortex development. In particular, I am interested in how the key transcription factor PAX6 drives glutamatergic fate in neural progenitors to ultimately generate functional glutamatergic neurons.
I employ multidisciplinary approaches including the cutting-edge single-cell transcriptomics, bioinformatics, organotypic culture and pharmacological treatments to tackle the aforementioned question.
[Poster presentation] Tan KB, Kozic Z, Dobolyi D, Manuel M, Mason JO, Price DJ (2020) “Cell fate decision during the embryonic neocortex development” Cold Spring Harbor Laboratory Meeting – Epigenetics and Chromatin
[Poster presentation] Tan KB, Kozic Z, Dobolyi D, Manuel M, Mason JO, Price DJ (2020) “PAX6 regulates cell fate in the developing embryonic neocortex” 14th EMBL Conference – Transcription and Chromatin
[Poster presentation] Tan KB, Kozic Z, Dobolyi D, Manuel M, Mason JO, Price DJ (2020) “PAX6: a transcriptional guardian for glutamatergic fate in the developing neocortex” 12th FENS Forum of Neuroscience [link][video]
[Poster presentation] Tan KB, Kozic Z, Manuel M, Mason JO, Price DJ (2019) “Roles of PAX6 in glutamatergic fate specification during forebrain development” Developmental Biology Gordon Research Conference, Massachusetts, US.
[Poster presentation] Tan KB, Manuel M, Mason JO, Price DJ (2018) “Roles of PAX6 and migratory interneurons in cortical fate specification” 11th FENS Forum of Neuroscience, Berlin, Germany.
[Oral presentation and conference proceeding] Tan KB, Reed DM, Zetterqvist A, Nikolakopoulou Z, Toe Q, Kirkby NS, Mitchell JA (2016) “Safety screening for cytokine storm-inducing biologics using cryopreserved BOECs and PBMCs” Proceedings of the British Pharmacological Society. [link]