Injury and Repair
The Research Theme is exploring the cellular and molecular mechanisms that underpin cell and tissue differentiation, resilience to injury, and repair processes.
Highly differentiated tissues, such as the central nervous system, are constantly exposed to a variety of challenges.
These include mechanical injury, degeneration, inflammation, and uncontrolled growth. In this theme, groups cooperate to discover the cellular and molecular mechanisms that underpin cell and tissue differentiation, resilience to injury, and repair processes.
We employ a variety of cellular models, model organisms, and screening approaches. This maximises synergy between groups in making fundamental discoveries and expediting translation of these to clinical research.
Theme Lead: Dr Thomas Becker
|Becker, Catherina||Development and regeneration of the zebrafish nervous system|
|Becker, Thomas||Development and regeneration of the zebrafish nervous system|
|Brophy, Peter||Molecular and cell biology of axon-glia interactions in health and disease|
|Fowler, Jill||Mechanisms of neurodegeneration in stroke and dementia|
|Hall, Andrew||Chondrocytes, cartilage and osteoarthritis|
|Herrgen, Leah||Molecular and cellular mechanisms of brain repair|
|Paxton, Jennifer||Musculoskeletal tissue engineering|
|Ribchester, Richard||Development, plasticity, degeneration, and regeneration of neuromuscular connections.|
|Sieger, Dirk||Microglia-tumour interactions|
|Torsney, Carole||Somatosensory plasticity|
|Wyllie, David||Physiology and pharmacology of ion channels|
|Zhang, HongYan||Locomotor control and rhythm generation in simple animal model systems|