Aortic stenosis

Overview

In patients with aortic stenosis, we demonstrated that the electrocardiographic strain pattern associated with left ventricular hypertrophy is indicative of myocardial fibrosis. We described a risk prediction model for patients with aortic stenosis demonstrating the important role of myocardial fibrosis imaging in determining future events.

This formed the basis of the Sir Jules Thorn Award for Biomedical Research 2015 to Dr Marc Dweck, which has funded a multi-centre clinical trial of early surgery in patients with advanced asymptomatic aortic stenosis using MR-based T1-mapping techniques, to characterise the fibrosis progression associated with this disease.

Lead aortic stenosis researcher 

• Prof Edwin van Beek

To discuss new research & collaborative imaging projects with Edinburgh Imaging, please contact:

Research staff with an aortic stenosis focus

• Prof Marc Dweck
• Prof David Newby
• Prof Scott Semple
• Dr Michelle Williams

Funding organisations & groups

Organisations are listed alphabetically:

• British Heart Foundation
• Sir Jules Thorn Charitable Trust