The Brain Images of Normal Subjects (BRAINS) imagebank is a searchable, living database of images & clinical information across the human lifespan.
What is BRAINS?
- an integrated repository project / living imagebank
- hosted by the University of Edinburgh
- sponsored by the Scottish Imaging Network: A Platform for Scientific Excellence (SINAPSE) collaborators
- contains data from 808 healthy volunteers
- 15 to 81 years of age
- from 7 projects in 3 centres
- new data will be added when available
- additional completed & ongoing studies of normal individuals from 1st to 10th decades are in preparation & will be included as they become available
What is the BRAINS imagebank?
- an anonymised collection of images & associated clinical data collected from 'normal' individuals participating in research
- it includes several MR & structural sequences (e.g. T1, T2, T2* & FLAIR) available in DICOM (http://dicom.nema.org/)
- future addition of DTI planned
- images are linked to a wide range of ‘textual data’ including:
- medical history
- physiological measures (e.g. blood pressure)
- medication use
- cognitive ability
- perinatal information for pre- / post-natal subjects
- the imagebank can be searched to include or exclude ranges of these variables to create better estimates of ‘what is normal’ at different ages
What does BRAINS provide?
- sharing & archiving of detailed normal human brain imaging
- sharing & archiving of relevant phenotypic data
- data is already collected in studies of healthy volunteers across the life-course
- focus is in particular on extremes of age where variability is largest
- current emphasis on older age
- future plans to include perinatal imaging
- future plans to include other imaging which is under-represented in existing databanks
Developing an integrated image bank & metadata for large-scale research in cerebrovascular disease: our experience from the stroke image bank project. Frontiers ITC. 2016. doi.org/10.3389/fict.2016.00032
- A brain imaging repository of normal structural MRI across the life course: Brain Images of Normal Subjects (BRAINS). Neuroimage. 2017 144(B):299-304. doi: 10.1016/j.neuroimage.2016.01.027
- Improving data availability for brain image biobanking in healthy subjects: practice-based suggestions from an international multidisciplinary working group. NeuroImage. 2017 153:399-409. doi.org/10.1016/j.neuroimage.2017.02.030