Edinburgh Imaging Facility Radiochemistry

The Radiochemistry facility at the University of Edinburgh houses a cyclotron with supporting radiochemistry suites to create both GMP & research PET radiotracers.

Overview

We can produce radiochemicals labelled with PET isotopes (¹⁸F, ¹¹C & ¹⁵O).

This allows us to: 

• Conduct PET imaging experiments & autoradiography with chemically-identical compounds
• Develop fully translational tracers
• Adopt locally existing radiolabelled tracers to GMP standards, for use in human in clinical studies

From Jan-Mar 2019, we are expanding our production facility to increase capacity for GMP radiopharmaceutical delivery.

Location

The EIF Radiochemistry is co-located with our EIF QMRI which allows for close collaboration with & efficient transfer of radiochemicals to the:

• PET-MR 3.0T Siemens Healthcare & Biograph mMR (the only PET-MR system in Scotland)
• PET-CT 64 slice GE Healthcare & Discovery 710
• PET-CT 128 slice Siemens Healthcare Biograph mCT

The EIF Radiochemistry is also in very close proximity to our EIF Preclinical which also allows for close collaboration with & efficient transfer of radiochemicals to the:

• PET-CT Mediso nanScan

In addition to providing tracers for local use within the Edinburgh Imaging Facilities, we also supply more remote PET centres.

Expertise

In addition to the above, we have local expertise in:

• Data reconstruction
• Image analysis
• Kinetic modelling
• HPLC metabolite quantification including
  • Arterial blood sampling
  • Input function measurement