01 Jul 20. MEMORY-COVID study begins
Manganese-Enhanced magnetic resonance imaging of MyOcardial injuRY in COVID 19 (MEMORY- COVID) study launched at the EIF RIE.
Evidence that myocardial injury occurs in a large number of COVID-19 patients is growing.
COVID-19 patients can present with heart failure, but the probable underlying cause remains unknown & could be due to:
- Stress cardiomyopathy
- Acute coronary syndrome
- Coronary heart disease
- Myocardial injury related to multi-organ failure (Indirect)
The MEMORY-COVID study will improve our understanding of the underlying mechanisms which lead to myocardial injury & will impact how we manage COVID-19 patients in clinical practice.
The EMERGE (The Emergency Medicine Research Group Edinburgh) research team will identify recovered COVID-19 patients; medical teams will identify eligible inpatients.
All patients will undergo paired MR scans at the Edinburgh Imaging Facility RIE.
For safety precautions, we will scan COVID-19 patients at least 14 days after symptom onset; additionally, patients will have had to have been afebrile for at least 48 hours prior to scanning.
The study has joint funding from the BHF Pump Priming COVID Response Grant & Medical Research Council (MRC).
The MEMORY-COVID study is a single site study. However co-investigators include other members of the cardiovascular research team, as well as the ITU research team:
- Prof David Newby (CI)
- Dr Marc Dweck
- Dr Scott Semple
- Prof Nicholas Mills
- Prof Tim Walsh
- Dr Kenneth Baillie
- Dr Anne-Marie Docherty
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Manganese-Enhanced magnetic resonance imaging of MyOcardial injuRY in COVID 19 (MEMORY- COVID) study launched at the EIF RIE. @MarcDweck @TheBHF @The_MRC @HighSTEACS #MyocardialInjury #MR