The microPET/CT laboratory was established in 2014 and offers state-of-the-art facilities for molecular imaging research using different radiotracers, as well as, high resolution anatomical computed tomography (CT) images.
Resources available in the microPET/CT laboratory allow for in vivo imaging studies in rodents targeting different systems and various research questions, as well as, ex vivo/in vitro imaging of human tissue samples and organs.
- Mediso nanoPET/CT, Mediso Medical Imaging Systems, Budapest, Hungary
- Axial field of view (FOV): 28 cm
- PET spatial resolution: 1.02 mm (axial cFOV, FWHM)
- PET sensitivity: 8%
- CT spatial resolution: <30μm at 10% modulation transfer function (MTF)
The preclinical PET/CT imaging facilities are complemented by laboratories dedicated to cell, tissue and organ radiolabelling for subsequent tracking or imaging using the microPET/CT system.
Through our active collaboration with the radiochemistry department at the clinical research imaging centre (CRIC), a wide range of 18F- and 11C-labelled radiotracers can be produced on site for preclinical PET/CT imaging. Examples include:
- 18F-FDG for imaging glucose metabolism;
- 18F-NaF for imaging crystals of hydroxyapatite;
- 18F-L-Dopa for imaging dopamine turnover;
- 18F-Fluorocholine for imaging cellular membrane phospholipids;
Others available upon consultation.