Clinical research & trials
Clinical research - investigating the people affected by brain diseases - is a mainstay of CCBS research.
We recruit volunteers for a wide range of clinical research studies, all designed to find out more about brain disease and how to treat it, manage symptoms or improve quality of life.
All our clinical research is approved and carefully monitored by the appropriate ethics committees. All participants sign an informed consent before participating. Involvement in research will never affect the quality of care given.
Our clinical research frequently involves our other disease methodologies, particularly:
|Neuroprotective strategies for fetuses/neonates at risk of brain injury & poor developmental outcome (includes the Theirworld Edinburgh Birth Cohort)||neurodevelopment||James Boardman|
|Speak:Unique – voicebanking & voice reconstruction||motor neurone disease||Siddharthan Chandran|
|Cognition in multiple sclerosis: linked psychological testing and brain imaging (with Bak/Chandran)||multiple sclerosis||Peter Connick|
|Advanced ocular imaging as a window into the brain||degenerative eye disease||Baljean Dhillon|
|Structural & functional brain imaging in schizophrenia & other psychiatric disorders||psychiatric disorders||Stephen Lawrie|
|STRADL (Stratifying Resilience and Depression Longitudinally)||psychiatric disorders||Andrew McIntosh|
|Magnetic resonance imaging to examine brain function in Fragile X Syndrome||fragile X syndrome||Andrew McKechanie|
|Physical activity for stroke rehabilitation||stroke||Gillian Mead|
|Functional disorders in neurology||functional disorders||Jon Stone|
|Sleep disorders incluing narcolepsy, parasomnias and circadian rhythm disorders||sleep disorders||Renata Riha|
|Perivascular spaces in small vessel disease||cerebral small vessel disease||Joanna Wardlaw|
|SVDs@target||cerebral small vessel disease||Joanna Wardlaw|
|Contribution of vascular risk factors to dementia||Will Whiteley|
CCBS researchers lead or take part in many clinical trials, often large-scale international trials with thousands of participants. These trials are often expedited through our links with Pharma and our expertise in disease registers.
Edinburgh Stroke Trials is an umbrella organisation that manages academic randomised controlled trials initiated by investigators in Edinburgh, often in collaboration with others. The trials involve researchers and systems developed by the Stroke Research Group, Edinburgh Imaging, and the UKCRC-registered Edinburgh Clinical Trials Unit.
|CLOTS (Clots in Legs Or sTockings after Stroke)||stroke||Martin Dennis|
|IST-3 (Third International Stroke Trial)||stroke||Peter Sandercock|
|Click-East (testing an iPad app for children with autism)||autism||Sue Fletcher-Watson|