Completed studies and trials
An archive of key research studies & clinical trials undertaken in CCBS. This page is not intended to be comprehensive.
REstart or STop Antithrombotics Randomised Trial (RESTART) (2021)
RESTART tested whether antiplatelet therapy can be safely re-started in patients who have survived an intracerebral haemorrhage.
FOCUS trial - Fluoxetine Or Control Under Supervision (2019)
The FOCUS trial was a randomised controlled trial that aimed to find out whether fluoxetine given to people for six months after a stroke improves long-term recovery, even if they do not have depression.
The CLOTS trials - Clots in Legs Or sTockings after Stroke (2015)
CLOTS was a family of multicentre randomised controlled trials testing external compression devices (e.g.stockings and intermittent pneumatic compression) for deep vein thrombosis (DVT) prevention in acute stroke patients.
Third international stroke trial (IST-3) (2013)
IST-3 was a randomised controlled trial to assess the benefits and harms of intravenous thrombolysis with the clot-busting drug alteplase within 6 h of acute ischaemic stroke.
GALA Trial - General anaesthetic versus local anaesthetic for carotid surgery (2008)
GALA was a multicentre randomised trial assessing the relative risks of stroke, cardiac events and death following carotid endarterectomy under either general or local anaesthesia.
The FOOD Trials - Feed Or Ordinary Diet in stroke (2005)
The FOOD trial was a family of three multicentre trials to evaluate feeding policies in patients with a recent stroke.