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PRE-EMPT clinical trial

PRE-EMPT is a randomised multicentre trial to compare medical treatments to prevent recurrence of disease following surgical removal of endometriosis.

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To compare three treatment options (DMPA, LNG-IUS and COCP) with each other to determine which is the most effective at reducing the risk of recurrence of symptoms.


Women who are undergoing laparoscopy to determine whether pelvic pain is due to endometriosis.


Multi centre across the UK

Recruitment target

400 women

Recruitment for this trial is now complete – follow-up in progress

Contact details

Professor Andrew Horne – Andrew.Horne@ed.ac.uk