The research at EXPPECT Edinburgh is led by Professor Andrew Horne, Professor Philippa Saunders and Dr Lucy Whitaker.
Each group focuses on furthering understanding of the causes of chronic pelvic pain, endometriosis symptoms and the development of novel treatment strategies.
Find out more about their research below.
- Jackie Young (University PA) Email: Jackie.Young@ed.ac.uk Tel: +44 (0) 131 242 6988
- Fiona Elliot (NHS secretary) Email: firstname.lastname@example.org Tel: +44 (0) 131 242 2525
- Please contact Fiona Elliot regarding any personal clinical matters. Tel: +44 (0) 131 242 2525
- Email: Andrew.Horne@ed.ac.uk
- Andrew Horne Twitter feed
Chronic pelvic pain affects over 1 million UK women. Up to 50% will have underlying endometriosis but in the remainder no obvious cause is often identified. We have recently completed a large UK-wide multicentre trial to determine whether gabapentin, a drug commonly used to treat other chronic pain conditions, is an effective treatment for chronic pelvic pain specifically. We have also shown that the cells lining the pelvis are different in women with endometriosis, leading to an altered environment in the pelvis. Our ongoing work aims to investigate targeted therapies to re-establish a normal healthy pelvic environment and relieve endometriosis symptoms.
View Professor Andrew Horne's web page for more information.
My work with patient groups has identified that women with endometriosis want more effective medical treatments so that they can avoid repeated invasive surgeries and the unwanted side effects associated with current therapies. I believe that novel therapeutics targeting androgen receptors hold significant promise as a medical treatment for the symptoms associated with endometriosis. My team are working towards understanding the androgen-regulated processes relevant to the establishment, and maintenance of, endometriosis lesions and their interaction with pain pathways.
View Professor Philippa Saunders' web page for more information.
My role is at the interface between bench side research and translation into standard clinical care pathways, designing and delivering clinical trials using multiple modalities that produce outputs that are both clinically meaningful and address patient needs. These include repurposing non hormonal medical treatments to modify the pelvic environment and surgical trials to address management uncertainties in the operative treatment of endometriosis.
Research Insights: Tackling the pain of endometriosis
Professor Andrew Horne and Professor Philippa Saunders discuss their endometriosis research. Recorded on 17 February 2021.
- Video: Research Insights: Tackling the pain of endometriosis
- Research Insights: Tackling the pain of endometriosis. Professor Andrew Horne and Professor Philippa Saunders discuss research to tackle a difficult condition that affects one in ten women in the UK. Recorded 17/02/2021.