MRC Centre for Reproductive Health
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Dr Luca Cassetta

Biographical Information and research interest.

Dr Luca Cassetta

Principal Investigator, ESAT Fellow



The Queen’s Medical Research Institute
Edinburgh BioQuarter
47 Little France Crescent

Post Code
EH16 4TJ

Dr Cassetta obtained his PhD in immunology at the University of Milan, funded by studentships from the National Minister of Health and ANLAIDS.

Following a brief postdoc in tumour immunology at the Albert Einstein Medical College (NY, USA), funded by the AIRC/Marie Curie International Fellowship, he carried out a postdoc at the Centre for Reproductive health in the lab of Prof Jeffrey Pollard. 

He is now a principal Investigator in the MRC Centre for Reproductive Health.

Luca’s research focuses on investigating novel therapeutic strategies to modulate the tumour microenvironment in solid tumours, with a special focus on Tumor Associated Macrophages (TAMs). He has more than 13 years of research experience in human macrophage biology, clinical material handling, multicolor flow cytometry and genome wide studies.

He is an author of multiple publications in international scientific journals including Cancer Cell, Nature Communications, Journal of Experimental Medicine, Blood, Proceedings of the National Academy of Sciences and Nature Reviews Drug Discovery.

In 2018 he founded a University of Edinburgh spin off company with Prof Jeffrey Pollard, Macomics (, for which he was awarded the Innovation Prize cup 2019 as a young entrepreneur.


Dr Cassetta is the co-founder with Dr Kitamura, Dr Bain, Dr Mariani and Dr Jackson of the network macrophages@EDIUni (Twitter @MacEdiUni) , whose main goal is to connect all the scientist working on macrophages at the University, in order to share material, protocols, knowledge and opinions.

Luca was also the UK representative and the Working Group 1 leader of COST Action BM1404 Mye-EUNITER, aimed at the standardization of markers and techniques for Myeloid Derived Suppressor Cells (MDSC) study (


Public engagement

Founder and current President of AIRIcerca, the society of Italian Researchers in the World. The AIRIcerca network includes more than 23000 Italian researchers around the World. The society provides different services such as mentoring, travel grants and psychological counselling (recently acknowledged by Nature to the academic researchers.

AIRIcerca has two main public outreach programs:  AIRInforma, the first peer-reviewed public engagement journal in Italy ( and AIRI-CLIP, a database of peer reviewed summaries of the latest studies on COVID19, created to tackle the SARS-COV-2 pandemic  (

The society has multiple chapters in Europe and North America and organizes networking events and public seminars called AIRItalks.


Twitter: @Airi_Talk

Recent publications

View Dr Luca Cassetta's publications on PubMed