MRC Centre for Reproductive Health
MRC Logo JAN 2019

Dr Jackie Maybin

Research interests and current grants.

Dr Jackie Maybin

Contact details

Address

Street

The Queen's Medical Research Institute
Edinburgh BioQuarter
47 Little France Crescent
Edinburgh
EH16 4TJ

Research interests

Our current research focuses on the physiology of menstruation and the aberrations that lead to problematic periods. We have a particular interest in the cause of heavy menstrual bleeding, a condition that has a severe negative impact on the quality of life of many women. We study the role of hypoxia during menstruation, particularly during the repair of the denuded endometrial surface. Our aim is to develop new, acceptable treatments for women with heavy periods to minimise the need for fertility removing surgery.

As an early career researcher, I work with support and mentorship from Professor Hilary Critchley.

View Professor Hilary Critchley's profile.

Current Grants

  • Maybin JA, Walmsley S, Saunders PKT, Weir C, Carmeliet P, Pollard J, Critchley HOD. Examining physiological hypoxia at menstruation to define the mechanisms that underpin endometrial resilience and heavy menstrual bleeding.
  • Wellcome Trust Clinical Research Career Development Fellowship,  £1 107 751. August 2019 to August 2024.
  • Maybin JA, Critchley HOD, Kershaw L, Mcnaught G. Does increased endometrial perfusion and lack of hypoxia at menstruation lead to heavy menstrual bleeding?  Wellbeing of Women Project Grant, 2016-2019, £179 486

Recent Grants

  • Maybin JA, Webb D, Critchley HOD. Is hypoxia required for hypoxia-inducible factor stabilisation at menstruation to drive efficient endometrial repair and limit menstrual blood loss? Academy of Medical Sciences Starter Grant for Clinical Lecturers, 2015-2017, £29 992
  • Maybin JA, Saunders PTK, Hirani N, Critchley HOD. The role of hypoxia inducible factor in endometrial repair. Wellcome Trust Early Postdoctoral Training Fellowship for Clinician Scientists 2013-2015, £240 147
  • Maybin JA. Vascular Endothelial Growth Factor (VEGF) as a treatment for Heavy Menstrual Bleeding (HMB). Institutional Strategic Support Fund (ISSF2), 2015-2016 £8 283

Media interest/Public engagement

BBC Radio 5 Live. https://www.thenakedscientists.com/podcasts/short/what-causes-heavy-periods

New Scientist https://www.newscientist.com/article/2096346-womens-heavy-periods-could-be-explained-by-missing-protein/

Research in a nutshell.

Radio 4 “Leading Edge” interview on their program on Funding Research, 2009. http://www.bbc.co.uk/programmes/b00mwwgc

Max Perutz/Guardian science writing prize, 2009 http://www.guardian.co.uk/education/2009/aug/31/max-perutz-science-writing-prize.

Staff/Group members

  • Kate Walker
  • Ms Lucy Smith (clinical research nurse)

Principle Collaborators

  • Hilary Critchley (CRH)
  • Jeff Pollard (CRH)
  • Nik Hirani (CIR)
  • Philippa Saunders (CIR)
  • Sarah Walmsley (CIR)
  • Peter Carmeliet (VRC, KU Leuven, Belgium)