MRC Centre for Reproductive Health
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Dr Jacqueline Maybin

Research interests and current grants.

Dr Jackie Maybin

Contact details



The Queen's Medical Research Institute
Edinburgh BioQuarter
47 Little France Crescent
EH16 4TJ

Research interests

Our mission is to develop preventive and therapeutic strategies for abnormal uterine bleeding (problematic periods). We aim to improve the quality of life of women, which will ultimately benefit wider society.

To achieve this, our clinical team and discovery scientists perform innovative research to enhance understanding of menstruation and associated disorders, collaborate globally, train the next generation of experts and engage with the public.

We have a particular interest in the cause of heavy menstrual bleeding, which has a severe negative impact on the quality of life of many women. We study the role of hypoxia during menstruation, particularly during the repair of the denuded endometrial surface. Our aim is to develop new, acceptable treatments for women with heavy periods to minimise the need for fertility removing surgery.

Visit the Healthy Optimal Period for Everyone (HOPE) website

Current Grants

  • Maybin JA, Walmsley S, Saunders PKT, Weir C, Carmeliet P, Pollard J, Critchley HOD. Examining physiological hypoxia at menstruation to define the mechanisms that underpin endometrial resilience and heavy menstrual bleeding. Wellcome Trust Clinical Research Career Development Fellowship. £1 107 751. August 2019 to August 2024.
  • Maybin JA (PI). The effect of the menstrual cycle on longer-term symptoms of COVID-19. Royal Society of Edinburgh Research Reboot (COVID-19 Impact) Research Grant. £24 831.40. May 2021 to Nov 2021.

Recent Grants

  • Maybin JA Tenovus Scotland Pilot Grant. The role of hypoxia in miRNA regulation at menstruation to influence menstrual blood loss. £19 644. Sept 2019-May 2020.
  • Maybin JA, Critchley HOD, Kershaw L, Mcnaught G. Does increased endometrial perfusion and lack of hypoxia at menstruation lead to heavy menstrual bleeding?  Wellbeing of Women Project Grant, 2016-2019, £179 486
  • Maybin JA, Webb D, Critchley HOD. Is hypoxia required for hypoxia-inducible factor stabilisation at menstruation to drive efficient endometrial repair and limit menstrual blood loss? Academy of Medical Sciences Starter Grant for Clinical Lecturers, 2015-2017, £29 992
  • Maybin JA, Saunders PTK, Hirani N, Critchley HOD. The role of hypoxia inducible factor in endometrial repair. Wellcome Trust Early Postdoctoral Training Fellowship for Clinician Scientists 2013-2015, £240 147

Media interest/Public engagement

BBC Radio 5 Live

Scotsman, 2020

RSE YAS Covid-19 Blog

New Scientist 

Research in a nutshell

Max Perutz/Guardian science writing prize, 2009 

Staff/Group members

  • Rocio Martinez Aguilar, Postdoctoral Researcher
  • Clinical Research Nurse

Principle Collaborators

  • Hilary Critchley (CRH)
  • Jeff Pollard (CRH)
  • Nik Hirani (CIR)
  • Philippa Saunders (CIR)
  • Sarah Walmsley (CIR)
  • Peter Carmeliet (VRC, KU Leuven, Belgium)

Current external activities

  • Member of the Royal Society of Edinburgh’s Young Academy of Scotland and Grand Challenge Lead for ‘Ending health inequalities’
  • Associate editor of ‘Reproduction’ Bioscientifica
  • Associate editor of ‘Frontiers in Reproduction’ (Non-malignant Gynaecology)
  • Faculty member of Faculty Opinions (Menstrual Abnormalities and Abnormal Uterine Bleeding)
  • Early Career Editorial Board Member of ‘Physiological Reviews’