MRC Centre for Reproductive Health

Dr Fiona Denison

Research interests, current research projects and grants.

Dr Fiona Denison

Senior Lecturer/Honorary Consultant in Maternal and Fetal Medicine

Contact details

Address

Street

The Queen’s Medical Research Institute
47 Little France Crescent

City
Edinburgh
Post Code
EH16 4TJ

Research Interests

My current research interests are in the area of maternal and fetal health. I currently have three main areas of research (i) the effect of maternal obesity on pregnancy outcome; (ii) the maternal cardiovascular adapation to pregnancy, and how this becomes perturbed in conditions such as pre-eclampsia and (iii) developing novel methods of imaging the placenta and fetus during pregnancy.

Visit the Jennifer Brown Research Laboratory web page

Current research projects

  • Prokineticin-1 receptor antagonist – evaluating its use as a novel therapeutic agent for preterm labour
  • Contraceptive choices after childbirth amongst women of different body mass index groups
  • Does metformin reduce excess birthweight in offspring of obese pregnant women? A randomised controlled trial of efficacy, exploration of mechanisms and evaluation of other pregnancy complications
  • Evaluating the use of MRI at 3T in pregnancy – pilot feasibility
  • Placental function in pregnancies complicated by maternal obesity
  • Investigating vascular function in obese and lean pregnant women
  • Temporal trends, outcomes and economic impact of maternal obesity in Scotland.
  • A Multi-Method Assessment of Barriers to Breastfeeding in Obese Women.

Grants

  • Norman, JE, Denison FC, Calder AA, Saunders PT, Seckl JR, Walker BR et al; £370,000; Tommy’s Centre for Maternal and Fetal Research Denison FC, Jabbour HN, Norman JE. Jennifer Brown Post-Doctoral Fellowship to Marta Gorowiec. 2009 – 2011; £109,130
  • Denison FC, S Forbes et al. Establishment of panlothian aquanatal exercise classes for obese pregnant women – a multidisciplinary Partnership approach; £12,100
  • Jabbour HN, Denison FC, Norman, JE, Catalano R. Prokineticin-1 receptor antagonist – a novel therapeutic agent for preterm labour? MRC Development Gap Funding,  2009 – 2011.     £150,000
  • Norman JE, Walker BR, Denison FC, Reynolds, Forbes S and 6 others. Does metformin reduce excess birthweight in offspring of obese pregnant women? A randomised controlled trial of efficacy, exploration of mechanisms and evaluation of other pregnancy complications. MRC Efficacy and Mechanism 2010 – 2013. £1,060,187
  • McKennzie G, Denison FC, Katikreddi V, et al. Prevalence of Influenza A (H1N1) in Professionals and Pregnancy In NHS Lothian (PIPPIN). CSO. 2009 – 2010 £117,088
  • Denison FC, Price J, Norman JE, Chalmers J et al. Temporal trends, outcomes and economic impact of maternal obesity in Scotland. CSO, 2010 – 2011 2009£49,995
  • Cameron ST, Denison FC. Contraceptive choices after childbirth amongst women of different body mass index groups. Barbour Watson Trust; £3,020
  • Denison FC, Keely A, Napier K, McCoy M, Swanson V. A Multi-Method Assessment of Barriers to Breastfeeding in Obese Women. CSO NHS Health Services Research; £62,000; 2011 – 2012
  • Denison FC. Applying established imaging techniques to the novel field of evaluating uteroplacental physiology and pathology in pregnancy – a pilot study. Albert McKern Fellowship Grant; £12,500

Staff/group members

  • Kathryn Carruthers
  • Hilary Guthrie

Principal collaborators

Responsibilities

Teaching commitments

  • University of Edinburgh Year 4 Undergraduate Obstetrics and Gynaecology Coordinator
  • Lunchtime tutorials for Yr 4 students (6 tutorials/year)
  • Lecture on Yr 4 core week (Labour and delivery; 3 sessions/year)
  • Lecture on Yr 4 revision week (Haemorrhage; 3 sessions/year)
  • Lecture on Reproductive Biology Honours Course (1x2hr lecture/year)
  • Lecturer on DRCOG course
  • Teach on HDU course (1/2 per year)
  • Teach on Obstetric Emergency Study Day (1/2 per year)
  • Provide Registrar Teaching Session (1/2 per year; critical appraisal)

Examiner

  • University of Edinburgh Year 4 Undergraduate Obstetrics and Gynaecology Examiner (3 exams per year)
  • External examiner for MD student

Set and Mark exam questions for:

  • 2nd year MBChB Reproductive biology
  • 4th year MBChB (Set 2 OSCE, 4 OSCA questions)
  • Reproductive Biology BSc Honours  (2 questions)

Student supervision for projects

  • BSc reproductive biology Hons (2010) (5 students)
  • SSC4 students (7 students)
  • MSc student (1 student)

Management activities

  • Member of Jennifer Brown Steering group
  • Member of Tommys Steering group
  • Principal Investigator and supervise/co-supervise students / research midwives
  • Member of CRB seminar organising committee
  • Member of medical student exclusion panel
  • Administration required for clinical commitments
  • Secretary of Blair Bell Research Society

Supervise student research projects

  • BSc Reproductive Biology Hons (2010) (5 students)
  • SSC4 students (7 students)
  • MSc student (1 student)

Supervise research midwife

  • Ethics and R&D applications (3 new ethics applications)
  • Caldicott applications (2 new applications)