Pippa Thomson Research Group

Section: Genomic Medicine

Research in a Nutshell

We are using genetics to understand how the brain controls behaviour through studying genetic susceptibility to psychiatric illness (depression, bipolar disorder and schizophrenia). The group combines both genetic, statistical and molecular approaches to understand the genetic basis of major mental illness. We continue this work, using linkage, association and whole genome sequence analysis to identify risk variants for mental illness and related quantitative traits such as cognition and mood, in both clinical and population-based cohorts. Key to this is using bioinformatics to understand the biological processes affected and integrating our understanding of the interaction between genetic and environmental effects acting on these complex phenotypes.

Contact

Pippa.Thomson@igmm.ed.ac.uk 

Collaborations

• Professor Andrew Mcintosh, University of Edinburgh 
• Professor Stephen Lawrie, University of Edinburgh 
• Professor Richard W. McCombie, Cold Spring Harbor, New York