Centre for Genomic & Experimental Medicine
Centre for Genomic & Experimental Medicine

Yanick Crow Research Group

Genetic disorders of Human Neurological and Immune Function

Professor Yanick Crow
Professor Yanick Crow

Section: Genome Medicine 

Research in a Nutshell

Yanick Crow is a clinician scientist, with the work of the Crow group driven by an interest in human diseases and a determination to improve their diagnosis and treatment.

The laboratory works across two themes: one relating to Aicardi-Goutières syndrome (AGS) and other disorders associated with enhanced type I interferon signalling (the so-called type I interferonopathies); and the second dedicated to an understanding of the causes of calcium in the brain (intracranial calcification), with a particular focus on two rare genetic conditions - leukoencephalopathy with calcifications and cysts (LCC) and Coats plus.

More information about these projects can be found by following the links below.

 

Aicardi-Goutières syndrome and the type I interferonopathies

 

LCC and Coats plus

 

Yanick Crow group

 

People

Yanick Crow Group Leader
Nathalie Blair Research Assistant
Marine Depp Research Assistant
Carolina Uggenti Post-doctoral Research Associate

Contact

yanick.crow@igmm.ed.ac.uk

 

Collaborations

  • Dr David Hunt, University of Edinburgh 
  • Professor Colin Smith, University of Edinburgh
  • Professor Adrian Hayday, King’s College, London 
  • Dr Gillian Rice, University of Manchester
  • Dr Darragh Duffy, Institut Pasteur, Paris
  • Professor Bénédicte Neven, Hôpital Necker Enfants Malades, Paris
  • Professor Stéphane Blanche, Hôpital Necker Enfants Malades, Paris
  • Dr Brigitte Bader-Meunier, Hôpital Necker Enfants Malades, Paris
  • Dr Marie-Louise Frémond, Institut Imagine, Paris
  • Dr Isabelle Melki, Institut Imagine, Paris

Partners and Funders

  • European Research Council
  • European Leukodystrophy Association

Scientific Themes

Genetics, Neurology, Immunology

Technology Expertise

Mendelian gene identification, Biomarker development, Clinical trials