Centre for Genomic & Experimental Medicine
Centre for Genomic & Experimental Medicine

Research Groups

Using genetics and genomics to diagnose, understand and better treat disease

Consistent with our mission to use genetics and genomics to understand the mechanisms of disease and inform novel intervention strategies, our research has a broad focus that spans the full spectrum of single gene inherited forms of disease, such as cystic fibrosis, to common causes of ill health in adulthood that also have a genetic component, such as bone and joint disease.

Our research is broadly grouped within two research sections, Genetic and Experimental Medicine and Translational Epidemiology.

Cathy Abbott Research Group

C.Abbott research
Translation factors in neurodevelopmental disorders and neurodgeneration

Tim Aitman Research Group

T.Aitman research
Diagnosis of rare recessive disease by exome sequencing

Omar Albagha Research Group

O.Albagha research
Genetic Determinants of Bone disease

Peter Bankhead Research Group

BioImage Analysis and Digital Pathology

Chris Boyd Research Group

C.Boyd research
Development of pulmonary gene therapy approaches to treat cystic fibrosis and other genetic diseases

Sara Brown Research Group

Molecular and genetic mechanisms in atopic eczema

Helen Colhoun Research Group

Diabetes Medical Informatics and Epidemiology

Kathy Evans Research Group

K.Evans research
Genetic and Functional Analysis of Neuropsychiatric Illness

Erika Kague Research Group

Images from Erika Kague's research
Molecular and cellular mechanisms in bone health and diseases

Charlie Lees Research Group

C.Lees Research
Uncovering the causes of consequences of inflammatory bowel disease by studying the role of genes, the environment, diet and microbiota and their inter-relationships in gut health and disease

Riccardo Marioni Research Group

Riccardo Marioni research
Genetics and epigenetics of cognitive ageing

Stuart Ralston Research Group

S.Ralston research
Pathogenesis and management of rheumatic and bone diseases

Pippa Thomson Research Group

P. Thomson research
The genetics of mental health and cognition

Generation Scotland Research Group

Generation Scotland
A family and population based cohort study for research into the genetic, environmental and sociodemographic influences on health over the life-course

David Porteous Research Group (Emeritus)

D.Porteous research
Identification of risk factors, disease processes and new treatments for common genetic disorders

Neil Carragher (Affiliate)

Cancer Research UK Edinburgh Centre  lab
Advancing drug discovery through high-content phenotypic and pathway profiling technologies

Yanick Crow (Affiliate)

Genetic disorders of Human Neurological and Immune Function

Sandi Deans (Affiliate)

Provide external quality assessment and educational material for end to end genomic testing for laboratories and clinical genetics centres globally to promote good practice, standardisation and patient safety through Genomics Quality Assessment (GenQA)

Helen Harris (Affiliate)

Wire-loop lesions in systemic lupus erythematosus
Systemic Lupus Erythematosis patient observational studies, fatigue management research, interventional pharma led studies.

Barbara Hauser (Affiliate)

Translational and clinical aspects of osteoimmunology; osteoporosis pathogenesis and treatment

Peter Kind (Affiliate)

Image depicting Professor Kind's abstract
Examining cellular and circuit dysfunction associated with monogenic forms of autism and intellectual disability.

Andrew McIntosh (Affiliate)

A.McIntosh research
Using genetic discoveries to identify the mechanisms of mental illness and resilience

Paul McKeigue (Affiliate)

Figure from "Persistent C-peptide secretion in Type 1 diabetes and its relationship to the genetic architecture of diabetes"
Methods for molecular and genetic epidemiology, with applications in clinical prediction and personalised medicine

Gerry McLachlan (Affiliate)

Respiratory gene therapy. Preclinical large animal safety/efficacy studies

Iain Nixon (Affiliate)

Diagram showing stage T1 nasal cancer
ENT surgeon with an interest in academic medicine

Philip Riches (Affiliate)

P.Riches research
Improving the care and understanding of gout, and exploring the pathogenesis of osteoporosis

Daniel Smith (Affiliate)

Genomic and data science approaches to understanding the pathophysiology of bipolar disorder

Athina Spiliopoulou (Affiliate)

Using statistical methods to answer questions on the pathogenesis, progression and treatment of disease.

Jason Swedlow (Affiliate)

Tools and capabilities for sharing, accessing and integrating multi-dimensional bioimaging and biomolecular data

Veronique Vitart (Affiliate)

V.Vitart research
From Gene to Function

Heather Whalley (Affiliate)

H.Whalley research
The integration of human psychiatric neuroimaging with genetics (common and rare variants), epigenetics, and stem cell models, in the context of clinically-relevant research

Jim Wilson (Affiliate)

J.Wilson research
Genetics of complex traits in isolated populations