Centre for Genomic & Experimental Medicine
Centre for Genomic & Experimental Medicine

Research Groups

Using genetics and genomics to diagnose, understand and better treat disease

Consistent with our mission to use genetics and genomics to understand the mechanisms of disease and inform novel intervention strategies, our research has a broad focus that spans the full spectrum of single gene inherited forms of disease, such as cystic fibrosis, to common causes of ill health in adulthood that also have a genetic component, such as bone and joint disease.

Our research is broadly grouped within three research sections:

Research Sections

Genome Medicine

Genetic analysis of complex traits and monogenic diseases in humans, utilising state-of-the-art sequencing technologies and computational analyses, such as whole genome and epigenome data and information to predict, diagnose and treat human disease.

Section Head: Professor Tim Aitman

Medical Genetics

Population genetics with a focus is on 'complex’ disorders of the brain, gene mutations that directly cause medical conditions such as ciliopathies, and novel gene therapies for Cystic Fibrosis.

Section Head: Professor David Porteous

Rheumatology & Bone Disease

Conducting basic, translational and clinical studies to gain greater understanding of the mechanisms that cause bone and joint diseases and apply this knowledge in clinical practice to benefit patients through new diagnostics and new treatments.

Section Head: Professor Stuart Ralston


Cathy Abbott Research Group

C.Abbott research
Translation factors in neurodevelopmental disorders and neurodgeneration

Tim Aitman Research Group

T.Aitman research
Diagnosis of rare recessive disease by exome sequencing

Omar Albagha Research Group

O.Albagha research
Genetic Determinants of Bone disease

Peter Bankhead

BioImage Analysis and Digital Pathology

Chris Boyd Research Group

C.Boyd research
Development of pulmonary gene therapy approaches to treat cystic fibrosis and other genetic diseases

Helen Colhoun Research Group

Diabetes Medical Informatics and Epidemiology

Yanick Crow Research Group

Genetic disorders of Human Neurological and Immune Function

Ashish Dhir Research Group

Nucleic acid metabolism and innate immunity

Kathy Evans Research Group

K.Evans research
Genetic and Functional Analysis of Neuropsychiatric Illness

Charlie Lees Research Group

C.Lees Research
Uncovering the causes of consequences of inflammatory bowel disease by studying the role of genes, the environment, diet and microbiota and their inter-relationships in gut health and disease

Riccardo Marioni Research Group

Riccardo Marioni research
Genetics and epigenetics of cognitive ageing

Kirsty Millar Research Group

K.Millar research
Identifying potential disease pathways in psychiatry through investigation of the effects of a t(1;11) translocation linked to major mental illness

David Porteous Research Group

D.Porteous research
Identification of risk factors, disease processes and new treatments for common genetic disorders

Stuart Ralston Research Group

S.Ralston research
Pathogenesis and management of rheumatic and bone diseases

Bernard Ramsahoye Research Group

B.Ramsahoye research
The Genetics and Epigenetics of Haematological malignancy

Donald Salter Research Group

D.Salter research
Translating the Potential of Proteogenomics and Mesenchymal Stem Cell Theranostics for the Treatment of Musculoskeletal Disease

Generation Scotland Research Group

Generation Scotland
A bioresource of human biological samples and data, available for medical research. Data on ~30,000 Scottish participants in three research tissue banks

Pippa Thomson Research Group

P. Thomson research
The genetics of mental health and cognition

Athina Spiliopoulou (Affiliate)

Using statistical methods to answer questions on the pathogenesis, progression and treatment of disease.

Caroline Hayward Research Group (Affiliate)

C.Hayward Research Image
Quantitative Traits in Health and Disease

Andrew McIntosh Research Group (Affiliate)

A.McIntosh research
Using genetic discoveries to identify the mechanisms of mental illness and resilience

Philip Riches Research Group (Affiliate)

P.Riches research
Exploring the pathogenesis of osteoporosis, and improving the care and understanding of gout

Heather Whalley Research Group (Affiliate)

H.Whalley research
The integration of human psychiatric neuroimaging with genetics (common and rare variants), epigenetics, and stem cell models, in the context of clinically-relevant research